The immune and skeletal systems share a variety of molecules, including cytokines,
chemokines, hormones, receptors, and transcription factors. Bone cells interact with immune …

Bone undergoes continuous remodeling, which is homeostatically regulated by concerted
communication between bone-forming osteoblasts and bone-degrading osteoclasts …

Osteoporotic fractures are prevalent in society, and their incidence appears to be increasing
as the worldwide population ages. However, conventional bone repair materials hardly …

Osteoclasts are specialized cells derived from the monocyte/macrophage haematopoietic
lineage that develop and adhere to bone matrix, then secrete acid and lytic enzymes that …

Osteoclasts are multinucleated cells of monocyte/macrophage origin that degrade bone
matrix. The differentiation of osteoclasts is dependent on a tumor necrosis factor (TNF) family …

Hundreds of millions of people worldwide are affected by bone-related diseases, such as
osteoporosis and rheumatoid arthritis. Understanding the molecular mechanisms of bone …

All osteogenic cells (osteoclasts, osteoblasts) contribute individually to bone remodeling.
Their cellular interactions control their cellular activities and the bone remodeling intensity …

Bone homeostasis is preserved by the balance of maintaining between the activity of
osteogenesis and osteoclastogenesis. However, investigations for the osteoclastogenesis …

The past decade has seen an explosion in the field of bone biology. The area of bone
biology over this period of time has been marked by a number of key discoveries that have …

Bone‐related diseases, such as osteoporosis and rheumatoid arthritis, affect hundreds of
millions of people worldwide and pose a tremendous burden to health care. By deepening …