The respiratory tract is a complex organ system that is responsible for the exchange of
oxygen and carbon dioxide. The human respiratory tract spans from the nostrils to the lung …

Microorganisms coexist in a complex milieu of bacteria, fungi, archaea, and viruses on or
within the human body, often as multifaceted polymicrobial biofilm communities at mucosal …

ABSTRACT The expanded Human Oral Microbiome Database (eHOMD) is a
comprehensive microbiome database for sites along the human aerodigestive tract that …

Metagenomic next-generation sequencing (mNGS) offers an agnostic approach for
emerging pathogen detection directly from clinical specimens. In contrast to targeted …

Rationale: Many bacterial pathogens causing respiratory infections in children are common
residents of the respiratory tract. Insight into bacterial colonization patterns and microbiota …

Rationale: Perinatal and postnatal influences are presumed important drivers of the early-life
respiratory microbiota composition. We hypothesized that the respiratory microbiota …

Background Lower respiratory tract infections (LRTIs) are a leading cause of childhood
morbidity and mortality. Potentially pathogenic organisms are present in the respiratory tract …

The vast majority of systemic bacterial infections are caused by facultative, often antibiotic-
resistant, pathogens colonizing human body surfaces. Nasal carriage of Staphylococcus …

Microbial communities span many orders of magnitude, ranging in scale from hundreds of
cells on a single particle of soil to billions of cells within the lumen of the gastrointestinal …

Respiratory tract infections are a major global health concern, accounting for high morbidity
and mortality, especially in young children and elderly individuals. Traditionally, highly …