Pediatric patients with sickle cell disease (SCD) experience a range of medical
complications that result in significant morbidity and mortality. Recent advances in …

Sickle-cell disease is an autosomal recessive genetic disorder of hemoglobin that causes
systemic damage. Hypoxia is the main actor of sickle-cell disease. It initiates acutely the …

Sickle cell disease (SCD) refers to a group of inherited blood disorders with considerable
morbidity that causes severe pain, reduces life expectancy, and requires significant self …

Abstract 50 years ago, people with sickle cell disease (SCD) were discouraged from
becoming pregnant, but now most should be supported if they choose to pursue a …

Children with sickle cell disease (SCD) have an increased risk of sleep disordered breathing
(SDB) compared with the general pediatric population. There has been a growing research …

Background Sickle cell disease (SCD) is a genetic hemoglobinopathy with an incidence of
250–300,000 births per year worldwide. SCD leads to a diffuse vasculopathy which …

Sickle cell disease is the most common genetic hemoglobinopathy worldwide, characterized
by a single-nucleotide mutation that predisposes to hemoglobin polymerization and …

Sickle cell disease (SCD) is a hemoglobinopathy with a prevalence of 17 cases per 10,000
people among African Americans. It is characterized by a wide range of clinical …

Objective To evaluate the acceptability and safety profile of nocturnal long-term oxygen
therapy (LTOT) in children with sickle cell disease (SCD) and chronic hypoxaemia. Design …

Sickle cell disease (SCD) is an inherited disease resulted due to a single mutation in beta
globin gene. It changes normal red blood cells into sickle-shaped cells, just rendering their …