Oral squamous cell carcinoma (OSCC) is a commonly occurring head and neck cancer. It
has a high prevalence in certain parts of the world, and is associated with a high mortality …

Glioblastoma multiforme (GBM), the most common and aggressive primary brain tumor, has
a high mortality rate despite extensive efforts to develop new treatments. GBM exhibits both …

Pancreatic cancer is a highly lethal malignancy with few effective therapies. We performed
exome sequencing and copy number analysis to define genomic aberrations in a …

Normal cells are hijacked by cancer cells forming together heterogeneous tumor masses
immersed in aberrant communication circuits that facilitate tumor growth and dissemination …

The MET tyrosine kinase receptor (also known as the HGF receptor) promotes tissue
remodelling, which underlies developmental morphogenesis, wound repair, organ …

Semaphorins are membrane-bound or diffusible factors that regulate key cellular functions
and are involved in cell–cell communication. Most of the effects of semaphorins are …

The receptor tyrosine kinase c-MET and its ligand, hepatocyte growth factor (HGF), regulate
multiple cellular processes that stimulate cell proliferation, invasion and angiogenesis. This …

Background Many prediction tools for microRNA (miRNA) targets have been developed, but
inconsistent predictions were observed across multiple algorithms, which can make further …

The human umbilical cord that originates from the embryo is an extra-embryonic membrane
and the Wharton's jelly within it is a rich source of stem cells (hWJSCs). It is not definitely …

The neuropilins (Nrps) are multifunctional proteins involved in development, immunity and
cancer. Neuropilin-1 (Nrp1), or its homologue neuropilin-2 (Nrp2), are coreceptors that …