Interventional therapies for acute pulmonary embolism: current status and principles for the development of novel evidence: a scientific statement from the American …

J Giri, AK Sista, I Weinberg, C Kearon, DJ Kumbhani… - Circulation, 2019 - Am Heart Assoc
Pulmonary embolism (PE) represents the third leading cause of cardiovascular mortality.
The technological landscape for management of acute intermediate-and high-risk PE is …

A randomized trial of the optimum duration of acoustic pulse thrombolysis procedure in acute intermediate-risk pulmonary embolism: the OPTALYSE PE trial

VF Tapson, K Sterling, N Jones, M Elder… - JACC: Cardiovascular …, 2018 - jacc.org
Objectives: The aim of this study was to determine the lowest optimal tissue plasminogen
activator (tPA) dose and delivery duration using ultrasound-facilitated catheter-directed …

A prospective, single-arm, multicenter trial of ultrasound-facilitated, catheter-directed, low-dose fibrinolysis for acute massive and submassive pulmonary embolism …

G Piazza, B Hohlfelder, MR Jaff, K Ouriel… - Cardiovascular …, 2015 - jacc.org
Objectives This study conducted a prospective, single-arm, multicenter trial to evaluate the
safety and efficacy of ultrasound-facilitated, catheter-directed, low-dose fibrinolysis, using …

Thrombolysis for pulmonary embolism and risk of all-cause mortality, major bleeding, and intracranial hemorrhage: a meta-analysis

S Chatterjee, A Chakraborty, I Weinberg, M Kadakia… - Jama, 2014 - jamanetwork.com
Importance Thrombolytic therapy may be beneficial in the treatment of some patients with
pulmonary embolism. To date, no analysis has had adequate statistical power to determine …

Pulmonary embolism response to fragmentation, embolectomy, and catheter thrombolysis (PERFECT): initial results from a prospective multicenter registry

WT Kuo, A Banerjee, PS Kim, FJ DeMarco Jr, JR Levy… - Chest, 2015 - Elsevier
BACKGROUND Systemic thrombolysis for acute pulmonary embolism (PE) carries up to a
20% risk of major bleeding, including a 2% to 5% risk of hemorrhagic stroke. We evaluated …

[HTML][HTML] Systemic thrombolysis for pulmonary embolism: a review

C Martin, K Sobolewski, P Bridgeman… - Pharmacy and …, 2016 - ncbi.nlm.nih.gov
Systemic Thrombolysis for Pulmonary Embolism: A Review - PMC Back to Top Skip to main
content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …

Contemporary management and outcomes of patients with massive and submassive pulmonary embolism

E Secemsky, Y Chang, CC Jain, JA Beckman… - The American journal of …, 2018 - Elsevier
Background Few contemporary studies have assessed the management and outcomes of
patients with massive and submassive pulmonary embolism. Given advances in therapy, we …

Aspiration thrombectomy for treatment of acute massive and submassive pulmonary embolism: initial single-center prospective experience

JJ Ciampi-Dopazo, JM Romeu-Prieto… - Journal of Vascular and …, 2018 - Elsevier
Purpose To evaluate the feasibility of aspiration thrombectomy in patients with acute
massive or submassive pulmonary embolism (PE). Materials and Methods This prospective …

[HTML][HTML] Improved early right ventricular function recovery but increased complications with catheter-directed interventions compared with anticoagulation alone for …

ED Avgerinos, NL Liang, OM El-Shazly, C Toma… - Journal of Vascular …, 2016 - Elsevier
Objective The purpose of this study was to determine the short-term and midterm outcomes
of catheter-directed intervention (CDI) compared with anticoagulation (AC) alone in patients …

Pulmonary embolism: care standards in 2018

A Borohovitz, MD Weinberg, I Weinberg - Progress in Cardiovascular …, 2018 - Elsevier
Pulmonary embolism (PE) is a leading cause of cardiovascular mortality worldwide. Clinical
presentation can be diverse, and clinicians should have a high index of suspicion regarding …