Sensitivity analysis of in silico fluid simulations to predict thrombus formation after left atrial appendage occlusion

J Mill, V Agudelo, AL Olivares, MI Pons, E Silva… - Mathematics, 2021 - mdpi.com
Atrial fibrillation (AF) is nowadays the most common human arrhythmia and it is considered
a marker of an increased risk of embolic stroke. It is known that 99% of AF-related thrombi …

Turbulent blood dynamics in the left heart in the presence of mitral regurgitation: a computational study based on multi-series cine-MRI

L Bennati, V Giambruno, F Renzi, V Di Nicola… - … and Modeling in …, 2023 - Springer
In this work, we performed a computational image-based study of blood dynamics in the
whole left heart, both in a healthy subject and in a patient with mitral valve regurgitation. We …

[HTML][HTML] Frequency and Clinical Significance of Atrial Cavities in situ Thrombosis: A Large-Scale Study and Literature Review

A Cresti, P Baratta, E Aloia, F De Sensi… - Journal of …, 2023 - journals.lww.com
Background: Atrial tachyarrhythmias are the main cause of atrial thrombosis, and are usually
in the left appendage. The prevalence and causes of endocavitarian thrombosis have not …

Atrial fibrillation and mitral regurgitation: clinical performance of direct oral anticoagulants in a real-world setting

E Melillo, A Rago, R Proietti, E Attena… - Journal of …, 2020 - journals.sagepub.com
Background: Atrial fibrillation (AF) is the most common cardiac arrhythmia and is frequently
present in patients with mitral regurgitation (MR). Currently, there is a lack of real-world …

Mechanical concordance between left atrium and left atrial appendage in nonvalvular atrial fibrillation: can it be exploited to avoid transesophageal echocardiography …

A Sonaglioni, M Lombardo, GL Nicolosi… - … International Journal of …, 2022 - Springer
Transesophageal echocardiography (TEE) is the gold standard for assessing left atrial
appendage (LAA) mechanic and thrombosis (LAAT); however, TEE is a high-risk procedure …

Stroke in mitral valve prolapse: Risk factors and left atrial function in cryptogenic versus non-cryptogenic ischemic subtypes

F Calicchio, LJ Lim, D Cross, D Bibby, Q Fang… - Frontiers in …, 2023 - frontiersin.org
Background and purpose Mitral valve prolapse (MVP) has been associated with an
increased risk of ischemic stroke. Older age, thicker mitral leaflets, and significant mitral …

Effect of mitral regurgitation on thrombotic risk in patients with nonrheumatic atrial fibrillation: a new cha2ds2-vasc score risk modifier?

SL Van Laer, S Verreyen, KM Winkler, H Miljoen… - The American journal of …, 2021 - Elsevier
The current study assessed the effect of mitral regurgitation (MR) on thrombotic risk in
nonrheumatic atrial fibrillation (AF). AF carries a thrombotic risk related to left atrial blood …

[HTML][HTML] Effect of mitral regurgitation on stroke risk in patients with non-rheumatic atrial fibrillation

S Raposeiras-Roubin, P Dominguez-Erquicia… - Archives of …, 2022 - Elsevier
Background Atrial fibrillation (AF) carries a thrombotic risk related to blood stasis in the left
atrium. In patients with rheumatic valve disease and AF, the presence of severe mitral …

Left atrial thrombus—are all atria and appendages equal?

A Cresti, O Camara - Cardiac Electrophysiology Clinics, 2023 - cardiacep.theclinics.com
Modern science shows how much humans are alike, with 99.9% of genome of any 2
individuals being identical. The homogeneity in human organ's structure and function is not …

Turbulence and blood washout in presence of mitral regurgitation: a computational fluid-dynamics study in the complete left heart

L Bennati, V Giambruno, F Renzi, V Di Nicola… - bioRxiv, 2023 - biorxiv.org
In this work we performed a computational image-based study of blood dynamics in the
whole left heart, both in a healthy subject and in a patient with mitral valve regurgitation …