Interactions of oxidative stress and neurovascular inflammation in the pathogenesis of traumatic brain injury
PM Abdul-Muneer, N Chandra, J Haorah - Molecular neurobiology, 2015 - Springer
Traumatic brain injury (TBI) is a major cause of death in the young age group and leads to
persisting neurological impairment in many of its victims. It may result in permanent …
persisting neurological impairment in many of its victims. It may result in permanent …
Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis
P Deb, S Sharma, KM Hassan - Pathophysiology, 2010 - Elsevier
Stroke is a serious neurological disease, and constitutes a major cause of death and
disability throughout the world. The pathophysiology of stroke is complex, and involves …
disability throughout the world. The pathophysiology of stroke is complex, and involves …
[HTML][HTML] Targeting aquaporin-4 subcellular localization to treat central nervous system edema
Swelling of the brain or spinal cord (CNS edema) affects millions of people every year. All
potential pharmacological interventions have failed in clinical trials, meaning that symptom …
potential pharmacological interventions have failed in clinical trials, meaning that symptom …
Cerebrospinal fluid influx drives acute ischemic tissue swelling
INTRODUCTION Cerebrospinal fluid (CSF) covers and protects the brain from mechanical
injury. CSF also flows along an interconnected network of perivascular spaces surrounding …
injury. CSF also flows along an interconnected network of perivascular spaces surrounding …
Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications
JM Simard, TA Kent, M Chen, KV Tarasov… - The Lancet …, 2007 - thelancet.com
Focal cerebral ischaemia and post-ischaemic reperfusion cause cerebral capillary
dysfunction, resulting in oedema formation and haemorrhagic conversion. There are …
dysfunction, resulting in oedema formation and haemorrhagic conversion. There are …
Selective vulnerability of the hippocampus in brain ischemia
R Schmidt-Kastner, TF Freund - Neuroscience, 1991 - Elsevier
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Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage
JP Dreier, S Major, A Manning, J Woitzik… - Brain, 2009 - academic.oup.com
The term cortical spreading depolarization (CSD) describes a wave of mass neuronal
depolarization associated with net influx of cations and water. Clusters of prolonged CSDs …
depolarization associated with net influx of cations and water. Clusters of prolonged CSDs …
Mechanisms of cerebral edema in traumatic brain injury: therapeutic developments
JJ Donkin, R Vink - Current opinion in neurology, 2010 - journals.lww.com
Attenuating blood–brain barrier permeability has become a promising approach to
managing brain edema and associated swelling given that increases in cranial water …
managing brain edema and associated swelling given that increases in cranial water …
[HTML][HTML] The cellular mechanisms of neuronal swelling underlying cytotoxic edema
Cytotoxic brain edema triggered by neuronal swelling is the chief cause of mortality
following brain trauma and cerebral infarct. Using fluorescence lifetime imaging to analyze …
following brain trauma and cerebral infarct. Using fluorescence lifetime imaging to analyze …
[HTML][HTML] Spreading depolarization is not an epiphenomenon but the principal mechanism of the cytotoxic edema in various gray matter structures of the brain during …
JP Dreier, CL Lemale, V Kola, A Friedman… - …, 2018 - Elsevier
Spreading depolarization (SD) is a phenomenon of various cerebral gray matter structures
that only occurs under pathological conditions. In the present paper, we summarize the …
that only occurs under pathological conditions. In the present paper, we summarize the …