[HTML][HTML] Extracellular matrix in high-grade serous ovarian cancer: Advances in understanding of carcinogenesis and cancer biology

Y Brown, S Hua, PS Tanwar - Matrix Biology, 2023 - Elsevier
High-grade serous ovarian cancer (HGSOC) is notoriously known as the “silent killer” of post-
menopausal women as it has an insidious progression and is the deadliest gynaecological …

[HTML][HTML] Multi-target tyrosine kinase inhibitor nanoparticle delivery systems for cancer therapy

W Xu, C Ye, X Qing, S Liu, X Lv, W Wang, X Dong… - Materials Today Bio, 2022 - Elsevier
Abstract Multi-target Tyrosine Kinase Inhibitors (MTKIs) have drawn substantial attention in
tumor therapy. MTKIs could inhibit tumor cell proliferation and induce apoptosis by blocking …

[HTML][HTML] Facile synthesis and characterization of ZnO nanoparticles for studying their biological activities and photocatalytic degradation properties toward methylene …

AA Almehizia, MA Al-Omar, AM Naglah, MA Bhat… - Alexandria Engineering …, 2022 - Elsevier
Lately, attention to combustion synthesis has been encouraged owing to being cost-
effective, rapid, and produces samples with low crystallite sizes and/or different morphology …

Novel platinum nanoclusters activate PI3K/AKT/mTOR signaling pathway-mediated autophagy for cisplatin-resistant ovarian cancer therapy

M Zhang, H Yue, X Huang, J Wang, Z Li… - ACS Applied Materials …, 2022 - ACS Publications
Platinum (Pt)-based chemotherapy drugs such as cisplatin are the first line and core options
for the treatment of ovarian cancer (OC), while cisplatin resistance has a worse prognosis …

Cationic liposomes mediated transdermal delivery of meloxicam and ketoprofen: Optimization of the composition, in vitro and in vivo assessment of efficiency

DA Kuznetsova, LA Vasileva, GA Gaynanova… - International Journal of …, 2021 - Elsevier
New liposomes modified with pyrrolidinium surfactants containing a hydroxyethyl fragment
(C n PB, n= 12, 14, 16) were prepared for transdermal delivery of non-steroidal anti …

Salt‐inducible kinase 2‐triggered release of its inhibitor from hydrogel to suppress ovarian cancer metastasis

Y Hua, H Yin, X Liu, J Xie, W Zhan, G Liang… - Advanced …, 2022 - Wiley Online Library
Abstract Salt‐inducible kinase 2 (SIK2) is a promising target for ovarian cancer therapy due
to its critical role in tumorigenesis and progression. Currently available SIK2 inhibitors have …

Engineering chemotherapeutic-augmented calcium phosphate nanoparticles for treatment of intraperitoneal disseminated ovarian cancer

M Qiu, J Chen, X Huang, B Li, S Zhang… - … Applied Materials & …, 2022 - ACS Publications
Ovarian cancer is a common gynecologic malignancy with a high fatality rate. Intraperitoneal
chemotherapy has been proved as an efficient clinical treatment for disseminated ovarian …

Growth differentiation factor-15 promotes immune escape of ovarian cancer via targeting CD44 in dendritic cells

Y Gao, Y Xu, S Zhao, L Qian, T Song, J Zheng… - Experimental Cell …, 2021 - Elsevier
Immune escape is the main cause of the low response rate to immunotherapy for cancer,
including ovarian cancer. Growth differentiation factor-15 (GDF-15) inhibits immune cell …

[HTML][HTML] Polymeric nanoparticle delivery of combination therapy with synergistic effects in ovarian cancer

SL Levit, C Tang - Nanomaterials, 2021 - mdpi.com
Treatment of ovarian cancer is challenging due to late stage diagnosis, acquired drug
resistance mechanisms, and systemic toxicity of chemotherapeutic agents. Combination …

[HTML][HTML] Targeted drug conjugate systems for ovarian cancer chemotherapy

OD Ogundipe, O Olajubutu, SK Adesina - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Ovarian cancer is a highly lethal disease that affects women. Early diagnosis and treatment
of women with early-stage disease improve the probability of survival. Unfortunately, the …