Clinical biology of the pituitary adenoma
S Melmed, UB Kaiser, MB Lopes, J Bertherat… - Endocrine …, 2022 - academic.oup.com
All endocrine glands are susceptible to neoplastic growth, yet the health consequences of
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …
[HTML][HTML] The hypothalamic-pituitary-adrenal axis: development, programming actions of hormones, and maternal-fetal interactions
The hypothalamic-pituitary adrenal axis is a complex system of neuroendocrine pathways
and feedback loops that function to maintain physiological homeostasis. Abnormal …
and feedback loops that function to maintain physiological homeostasis. Abnormal …
[HTML][HTML] Single-cell transcriptomics identifies divergent developmental lineage trajectories during human pituitary development
S Zhang, Y Cui, X Ma, J Yong, L Yan, M Yang… - Nature …, 2020 - nature.com
The anterior pituitary gland plays a central role in regulating various physiological
processes, including body growth, reproduction, metabolism and stress response. Here, we …
processes, including body growth, reproduction, metabolism and stress response. Here, we …
Self-formation of functional adenohypophysis in three-dimensional culture
H Suga, T Kadoshima, M Minaguchi, M Ohgushi… - Nature, 2011 - nature.com
The adenohypophysis (anterior pituitary) is a major centre for systemic hormones. At
present, no efficient stem-cell culture for its generation is available, partly because of …
present, no efficient stem-cell culture for its generation is available, partly because of …
The paraventricular nucleus of the hypothalamus: development, function, and human diseases
C Qin, J Li, K Tang - Endocrinology, 2018 - academic.oup.com
The paraventricular nucleus of the hypothalamus (PVH), located in the ventral diencephalon
adjacent to the third ventricle, is a highly conserved brain region present in species from …
adjacent to the third ventricle, is a highly conserved brain region present in species from …
[HTML][HTML] Functional anterior pituitary generated in self-organizing culture of human embryonic stem cells
C Ozone, H Suga, M Eiraku, T Kadoshima… - Nature …, 2016 - nature.com
Anterior pituitary is critical for endocrine systems. Its hormonal responses to positive and
negative regulators are indispensable for homeostasis. For this reason, generating human …
negative regulators are indispensable for homeostasis. For this reason, generating human …
SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland
The pituitary gland adapts the proportion of each of its endocrine cell types to meet differing
hormonal demands throughout life. There is circumstantial evidence that multipotent adult …
hormonal demands throughout life. There is circumstantial evidence that multipotent adult …
Social stimuli induce activation of oxytocin neurons within the paraventricular nucleus of the hypothalamus to promote social behavior in male mice
Oxytocin (OT) is critical for the expression of social behavior across a wide array of species;
however, the role of this system in the encoding of socially relevant information is not well …
however, the role of this system in the encoding of socially relevant information is not well …
GnRH signaling, the gonadotrope and endocrine control of fertility
SP Bliss, AM Navratil, J Xie, MS Roberson - Frontiers in …, 2010 - Elsevier
Mammalian reproductive cycles are controlled by an intricate interplay between the
hypothalamus, pituitary and gonads. Central to the function of this axis is the ability of the …
hypothalamus, pituitary and gonads. Central to the function of this axis is the ability of the …
In vitro organogenesis in three dimensions: self-organising stem cells
Y Sasai, M Eiraku, H Suga - Development, 2012 - journals.biologists.com
Organ formation during embryogenesis is a complex process that involves various local cell-
cell interactions at the molecular and mechanical levels. Despite this complexity …
cell interactions at the molecular and mechanical levels. Despite this complexity …