Improvements in early interventions after acute myocardial infarction (AMI), notably, the
increased use of timely reperfusion therapy, have increased survival dramatically in recent …

Deficits in neuronal function are a hallmark of spinal cord injury (SCI) and therapeutic efforts
are often focused on central nervous system (CNS) axon regeneration. However, secondary …

In adult mammals, massive sudden loss of cardiomyocytes after infarction overwhelms the
limited regenerative capacity of the myocardium, resulting in the formation of a collagen …

Background: Inflammation is a key factor of myocardial damage in reperfused ST-segment–
elevation myocardial infarction. We hypothesized that colchicine, a potent anti-inflammatory …

Cardiac remodeling is defined as a group of molecular, cellular and interstitial changes that
manifest clinically as changes in size, mass, geometry and function of the heart after injury …

Toll-like receptors (TLRs) are a family of pattern recognition receptors involved in
cardiovascular diseases. Notably, numerous studies have demonstrated that TLR4 activates …

In the infarcted heart, the damage‐associated molecular pattern proteins released by
necrotic cells trigger both myocardial and systemic inflammatory responses. Induction of …

Mounting evidence suggests that therapeutic cell and drug delivery strategies designed to
actively harness the regenerative potential of the inflammatory response have great …

Rationale: Ca2+ homeostasis—a critical determinant of cardiac contractile function—is
critically regulated by SERCA2a (sarcoplasmic reticulum Ca2+-ATPase 2a). Our previous …

В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …