[HTML][HTML] Novel targets for immune-checkpoint inhibition in cancer
Immune-checkpoint inhibitors have revolutionized cancer therapy, yet many patients either
do not derive any benefit from treatment or develop a resistance to checkpoint inhibitors …
do not derive any benefit from treatment or develop a resistance to checkpoint inhibitors …
Biosensing chips for cancer diagnosis and treatment: a new wave towards clinical innovation
Recent technological advances in nanoscience and material designing have led to the
development of point-of-care devices for biomolecule sensing and cancer diagnosis. In situ …
development of point-of-care devices for biomolecule sensing and cancer diagnosis. In situ …
Nanomedicine strategies for heating “cold” ovarian cancer (OC): next evolution in immunotherapy of OC
Y Yang, T Zhao, Q Chen, Y Li, Z Xiao… - Advanced …, 2022 - Wiley Online Library
Immunotherapy has revolutionized cancer treatment, dramatically improving survival rates of
melanoma and lung cancer patients. Nevertheless, immunotherapy is almost ineffective …
melanoma and lung cancer patients. Nevertheless, immunotherapy is almost ineffective …
Tumor infiltrating lymphocytes (TILs) as a predictive biomarker of response to checkpoint blockers in solid tumors: a systematic review
D Presti, FG Dall'Olio, B Besse, JM Ribeiro… - Critical Reviews in …, 2022 - Elsevier
Immunotherapy is a standard of care in many solid tumors but many patients derive limited
benefit from it. There is increasing interest toward tumor infiltrating lymphocytes (TILs) since …
benefit from it. There is increasing interest toward tumor infiltrating lymphocytes (TILs) since …
A multi-organ-on-chip to recapitulate the infiltration and the cytotoxic activity of circulating NK cells in 3D matrix-based tumor model
The success of immunotherapeutic approaches strictly depends on the immune cells
interaction with cancer cells. While conventional in vitro cell cultures under-represent the …
interaction with cancer cells. While conventional in vitro cell cultures under-represent the …
Modelling acute myeloid leukemia (AML): What's new? A transition from the classical to the modern
A Dozzo, A Galvin, JW Shin, S Scalia… - Drug Delivery and …, 2023 - Springer
Acute myeloid leukemia (AML) is a heterogeneous malignancy affecting myeloid cells in the
bone marrow (BM) but can spread giving rise to impaired hematopoiesis. AML incidence …
bone marrow (BM) but can spread giving rise to impaired hematopoiesis. AML incidence …
Current challenges and practical aspects of molecular pathology for non-small cell lung cancers
The continuing evolution of treatment options in thoracic oncology requires the pathologist to
regularly update diagnostic algorithms for management of tumor samples. It is essential to …
regularly update diagnostic algorithms for management of tumor samples. It is essential to …
Epigenetics and metabolism reprogramming interplay into glioblastoma: novel insights on immunosuppressive mechanisms
F Torrisi, S D'Aprile, S Denaro, AM Pavone… - Antioxidants, 2023 - mdpi.com
The central nervous system represents a complex environment in which glioblastoma
adapts skillfully, unleashing a series of mechanisms suitable for its efficient development …
adapts skillfully, unleashing a series of mechanisms suitable for its efficient development …
Integrating Artificial Intelligence and PET imaging for drug discovery: A paradigm shift in immunotherapy
The integration of artificial intelligence (AI) and positron emission tomography (PET) imaging
has the potential to become a powerful tool in drug discovery. This review aims to provide an …
has the potential to become a powerful tool in drug discovery. This review aims to provide an …
DANCR deletion retards the initiation and progression of hepatocellular carcinoma based on gene knockout and patient-derived xenograft in situ hepatoma mice …
X Gan, D Ding, M Wang, Y Yang, D Sun, W Li, W Ding… - Cancer Letters, 2022 - Elsevier
Our previous study has demonstrated that the expression level of long noncoding RNA
(lncRNA)-differentiation antagonizing non-protein coding RNA (DANCR) increases in …
(lncRNA)-differentiation antagonizing non-protein coding RNA (DANCR) increases in …