Perioperative Management of Elderly patients (PriME): recommendations from an Italian intersociety consensus

P Aceto, R Antonelli Incalzi, G Bettelli, M Carron… - Aging Clinical and …, 2020 - Springer
Background Surgical outcomes in geriatric patients may be complicated by factors such as
multiple comorbidities, low functional performance, frailty, reduced homeostatic capacity …

Treatment of delirium in older persons: what we should not do!

F Lauretani, G Bellelli, G Pelà, S Morganti… - International journal of …, 2020 - mdpi.com
The presentation of common acute diseases in older age is often referred to as “atypical”.
Frequently, the symptoms are neither single nor tissue related. In most cases, the onset of …

Positive scores on the 4AT delirium assessment tool at hospital admission are linked to mortality, length of stay and home time: two-centre study of 82,770 emergency …

A Anand, M Cheng, T Ibitoye, AMJ Maclullich… - Age and …, 2022 - academic.oup.com
Background Studies investigating outcomes of delirium using large-scale routine data are
rare. We performed a two-centre study using the 4 'A's Test (4AT) delirium detection tool to …

Efficacy and Safety of Remimazolam Tosilate versus Dexmedetomidine for Sedation in Non-Intubated Older Patients with Agitated Delirium After Orthopedic Surgery …

Y Deng, Z Qin, Q Wu, L Liu, X Yang, X Ju… - Drug Design …, 2023 - Taylor & Francis
Purpose The purpose of the present study was to investigate the efficacy and safety of
remimazolam tosilate compared with dexmedetomidine for the relief of agitated delirium in …

Delirium superimposed on dementia

A Morandi, G Bellelli - European Geriatric Medicine, 2020 - Springer
Purpose Delirium superimposed on dementia (DSD) is a frequent and growing emerging
clinical challenge, given the increasing prevalence of dementia. Methods This narrative …

An interdisciplinary statement of scientific societies for the advancement of delirium care across Europe (EDA, EANS, EUGMS, COTEC, IPTOP/WCPT)

A Morandi, C Pozzi, K Milisen, H Hobbelen… - BMC geriatrics, 2019 - Springer
Background Delirium is a geriatric syndrome that presents in 1 out of 5 hospitalized older
patients. It is also common in the community, in hospices, and in nursing homes. Delirium …

A point prevalence study of delirium in Italian nursing homes

V Morichi, M Fedecostante, A Morandi… - Dementia and geriatric …, 2018 - karger.com
Background: Delirium is a common geriatric syndrome. Few studies have been conducted in
nursing home (NH) residents. The aim of this project was to perform a point prevalence …

Causal relationship between dementia and delirium: Insights from a bidirectional two-sample Mendelian randomization analysis

Y Cai, J Wang, X Wang, Q Yuan, Y Xu, P Xu - Journal of Affective Disorders, 2024 - Elsevier
Background Our previous study found dementia as a significant risk factor for delirium
development in elderly patients with hip fracture. However, the causal relationship between …

The frail patient undergoing cardiac surgery: lessons learned and future perspectives

M Pozzi, S Mariani, M Scanziani… - Frontiers in …, 2023 - frontiersin.org
Frailty is a geriatric condition characterized by the reduction of the individual's homeostatic
reserves. It determines an increased vulnerability to endogenous and exogenous stressors …

Visual and hearing impairment are associated with delirium in hospitalized patients: results of a multisite prevalence study

A Morandi, M Inzitari, C Udina, N Gual, M Mota… - Journal of the American …, 2021 - Elsevier
Objective Sensory deficits are important risk factors for delirium but have been investigated
in single-center studies and single clinical settings. This multicenter study aims to evaluate …