Ricin and Ricinus communis in pharmacology and toxicology-from ancient use and “Papyrus Ebers” to modern perspectives and “poisonous plant of the year 2018”
H Franke, R Scholl, A Aigner - Naunyn-Schmiedeberg's archives of …, 2019 - Springer
While probably originating from Africa, the plant Ricinus communis is found nowadays
around the world, grown for industrial use as a source of castor oil production, wildly …
around the world, grown for industrial use as a source of castor oil production, wildly …
Recent Advances in the Detection of Food Toxins Using Mass Spectrometry
Edibles are the only source of nutrients and energy for humans. However, ingredients of
edibles have undergone many physicochemical changes during preparation and storage …
edibles have undergone many physicochemical changes during preparation and storage …
Biological toxins of potential bioterrorism risk: Current status of detection and identification technology
BG Dorner, R Zeleny, K Harju, JA Hennekinne… - TrAC Trends in …, 2016 - Elsevier
Biological toxins are a heterogeneous group of compounds that share commonalities both
with biological and chemical agents. Based on their availability, toxicity, and the lack of …
with biological and chemical agents. Based on their availability, toxicity, and the lack of …
Top-down mass spectrometry for trace level quantification of staphylococcal enterotoxin A variants
D Lefebvre, F Fenaille, D Merda… - Journal of Proteome …, 2021 - ACS Publications
We addressed here the need for improved sensitivity of top-down mass spectrometry for
identification, differentiation, and absolute quantification of sequence variants of SEA, a …
identification, differentiation, and absolute quantification of sequence variants of SEA, a …
Rapid, sensitive and reliable ricin identification in serum samples using LC–MS/MS
L Feldberg, E Elhanany, O Laskar, O Schuster - Toxins, 2021 - mdpi.com
Ricin, a protein derived from the seeds of the castor bean plant (Ricinus communis), is a
highly lethal toxin that inhibits protein synthesis, resulting in cell death. The widespread …
highly lethal toxin that inhibits protein synthesis, resulting in cell death. The widespread …
Rapid detection of abrin toxin and its isoforms in complex matrices by immuno-extraction and quantitative high resolution targeted mass spectrometry
EM Hansbauer, S Worbs, H Volland, S Simon… - Analytical …, 2017 - ACS Publications
Abrin expressed by the tropical plant Abrus precatorius is highly dangerous with an
estimated human lethal dose of 0.1–1 μg/kg body weight. Due to the potential misuse as a …
estimated human lethal dose of 0.1–1 μg/kg body weight. Due to the potential misuse as a …
A simple, fast and portable method for electrochemical detection of adenine released by ricin enzymatic activity
G Oliveira, JM Schneedorf - Toxins, 2021 - mdpi.com
International authorities classify ricin toxin present in castor seed as a potential agent for use
in bioterrorism. Therefore, the detection, identification, and characterization of ricin in various …
in bioterrorism. Therefore, the detection, identification, and characterization of ricin in various …
An international proficiency test to detect, identify and quantify ricin in complex matrices
S Worbs, M Skiba, J Bender, R Zeleny, H Schimmel… - Toxins, 2015 - mdpi.com
While natural intoxications with seeds of Ricinus communis (R. communis) have long been
known, the toxic protein ricin contained in the seeds is of major concern since it attracts …
known, the toxic protein ricin contained in the seeds is of major concern since it attracts …
Ricin-like proteins from the castor plant do not influence liquid chromatography-mass spectrometry detection of ricin in forensically relevant samples
ED Merkley, SC Jenson, JS Arce, AM Melville… - Toxicon, 2017 - Elsevier
The toxic protein ricin (also known as RCA60), found in the seed of the castor plant (Ricinus
communis) is frequently encountered in law enforcement investigations. The ability to detect …
communis) is frequently encountered in law enforcement investigations. The ability to detect …
Highly sensitive MALDI-MS measurement of active ricin: Insight from more potential deoxynucleobase-hybrid oligonucleotide substrates
J Yang, C Wang, L Luo, Z Li, B Xu, L Guo, J Xie - Analyst, 2021 - pubs.rsc.org
Herein, we report an improved MALDI-MS method for active ricin to contribute toward
countermeasures against its real threat to the public. Compared with commonly used DNA …
countermeasures against its real threat to the public. Compared with commonly used DNA …