Herein we summarize important discoveries made over many years about Leydig cell
function and regulation. Fetal Leydig cells produce the high levels of androgen (testosterone …

Androgens are potent drugs requiring prescription for valid medical indications but are
misused for invalid, unproven, or off-label reasons as well as being abused without …

Male Infertility - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC
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An increasing number of patients require long-term medication regimens at a young age, but
the adverse effects of medications on male reproduction are often inadequately considered …

Male reproduction is a complex process, and numerous medical conditions have the
potential to alter spermatogenesis. In addition, male factor infertility may be a biomarker for …

Purpose: Although testosterone replacement therapy use in the United States has increased
dramatically in the last decade, to our knowledge trends in testosterone replacement therapy …

Evaluation of the azoospermic male: a committee opinion - ScienceDirect Skip to main
contentSkip to article Elsevier logo Journals & Books Search RegisterSign in View PDF …

Male reproduction is a complex biological process, and male factor infertility is increasingly
recognized as a biomarker for overall male health. Emerging data suggest associations …

Objective To determine factors that influence sperm recovery after T-associated infertility.
Design Clinical retrospective study. Setting Academic male-infertility urology clinic. Patient …

Testosterone biosynthesis progressively decreases in aging males primarily as a result of
functional changes to Leydig cells. Despite this, the mechanisms underlying steroidogenesis …