[HTML][HTML] Microbiota dysbiosis and barrier dysfunction in inflammatory bowel disease and colorectal cancers: exploring a common ground hypothesis

LCH Yu - Journal of biomedical science, 2018 - Springer
Inflammatory bowel disease (IBD) is a multifactorial disease which arises as a result of the
interaction of genetic, environmental, barrier and microbial factors leading to chronic …

Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation

AM Thomas, P Manghi, F Asnicar, E Pasolli… - Nature medicine, 2019 - nature.com
Several studies have investigated links between the gut microbiome and colorectal cancer
(CRC), but questions remain about the replicability of biomarkers across cohorts and …

[HTML][HTML] The NF-κB signaling pathway, the microbiota, and gastrointestinal tumorigenesis: recent advances

C Peng, Y Ouyang, N Lu, N Li - Frontiers in Immunology, 2020 - frontiersin.org
Gastrointestinal (GI) cancers, especially gastric cancer and colorectal cancer (CRC),
represent a major global health burden. A large population of microorganisms residing in …

[HTML][HTML] New insights into natural products that target the gut microbiota: Effects on the prevention and treatment of colorectal cancer

L Lu, J Dong, Y Liu, Y Qian, G Zhang, W Zhou… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is one of the most common malignant carcinomas. CRC is
characterized by asymptomatic onset, and most patients are already in the middle and …

[HTML][HTML] The microbiota and microbiome in pancreatic cancer: more influential than expected

MY Wei, S Shi, C Liang, QC Meng, J Hua, YY Zhang… - Molecular cancer, 2019 - Springer
Microbiota is just beginning to be recognized as an important player in carcinogenesis and
the interplay among microbes is greater than expected. Pancreatic ductal adenocarcinoma …

[HTML][HTML] The gut microbiota influenced by the intake of probiotics and functional foods with prebiotics can sustain wellness and alleviate certain ailments like gut …

D Dahiya, PS Nigam - Microorganisms, 2022 - mdpi.com
The gut microbiota is composed of several microbial strains, with diverse and variable
combinations in healthy and sick persons, changing at different stages of life. A healthy …

The microbial landscape of colorectal cancer

MT White, CL Sears - Nature Reviews Microbiology, 2024 - nature.com
Colorectal cancer (CRC) is a substantial source of global morbidity and mortality in dire
need of improved prevention and treatment strategies. As our understanding of CRC grows …

Curcumin and colorectal cancer: An update and current perspective on this natural medicine

W Weng, A Goel - Seminars in cancer biology, 2022 - Elsevier
Colorectal cancer (CRC) is one of most common malignancies worldwide and its incidence
is still growing. In spite of recent advances in targeted therapies, their clinical efficacy has …

Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice

JL Drewes, J Chen, NO Markham, RJ Knippel… - Cancer discovery, 2022 - AACR
Defining the complex role of the microbiome in colorectal cancer and the discovery of novel,
protumorigenic microbes are areas of active investigation. In the present study, culturing and …

[HTML][HTML] Microbiome in colorectal cancer: how to get from meta-omics to mechanism?

D Ternes, J Karta, M Tsenkova, P Wilmes, S Haan… - Trends in …, 2020 - cell.com
Mounting evidence from metagenomic analyses suggests that a state of pathological
microbial imbalance or dysbiosis is prevalent in the gut of patients with colorectal cancer …