Contrary to the initial belief that myofibroblasts are terminally differentiated cells,
myofibroblasts have now been widely recognized as an activation state that is reversible …

Fibroblasts are abundant stromal cells which not only control the integrity of extracellular
matrix (ECM) but also act as immune regulators. It is known that the structural cells within …

The objective of this study was to create a nanofiber-based skin graft with an antimicrobial
bandage that could accelerate the healing of an open wound while minimizing infection. To …

Inside the finger-like intestinal projections called villi, strands of smooth muscle cells contract
to propel absorbed dietary fats through the adjacent lymphatic capillary, the lacteal, sending …

Polycystic kidney disease (PKD) is characterized by extensive cyst formation and
progressive fibrosis. However, the molecular mechanisms whereby the loss/loss-of-function …

During the physiological healing of skin wounds, fibroblasts recruited from the uninjured
adjacent dermis and deeper subcutaneous fascia layers are transiently activated into …

Keratin materials are promising in wound healing acceleration, however, it is a challenge for
the keratin to efficiently therapy the impaired wound healing, such as diabetic foot ulcers …

Fibroblasts are integral to the organization and function of all organs and play critical roles in
pathologies such as fibrosis; however, we have limited understanding of the fibroblasts that …

Regeneration allows animals to replace and restore injured tissues. Animal phyla have
evolved different regenerative strategies to increase survival advantages. In contrast to the …

Abstract CXC chemokine receptor 6 (CXCR6), a seven-transmembrane domain G-protein-
coupled receptor, plays a pivotal regulatory role in inflammation and tissue damage through …