The oncogenic transcription factor signal transducer and activator of transcription 3 (STAT3)
is activated constitutively in a wide array of human cancers. It is an appealing molecular …

Aberrant activation of signal transducer and activator of transcription (STAT) proteins is
associated with the development and progression of solid tumors. However, as transcription …

Signal transducer and activator of transcription 5 (STAT5) is an attractive therapeutic target,
but successful targeting of STAT5 has proved to be difficult. Here we report the development …

The interleukin 23 (IL-23) is a key pro-inflammatory cytokine in the development of chronic
inflammatory diseases, such as psoriasis, inflammatory bowel diseases, multiple sclerosis …

Hepatocellular carcinoma (HCC) is one of the lethal and leading types of cancer threatening
the globe with a high mortality rate. STAT3 is an oncogenic transcription factor that is …

Molecular signaling pathways play a significant role in the regulation of biological
mechanisms, and their abnormal expression can provide the conditions for cancer …

Malaria is an ancient infectious disease that threatens millions of lives globally even today.
The discovery of artemisinin, inspired by traditional Chinese medicine (TCM), has brought in …

Leukemic cutaneous T‐cell lymphomas (L‐CTCL) are lymphoproliferative disorders of skin‐
homing mature T‐cells causing severe symptoms and high mortality through chronic …

Epithelial ovarian cancer (EOC) is the most lethal of all gynecologic malignancies. Despite
advances in surgical and chemotherapeutic options, most patients with advanced EOC have …

Signal transducer and activator of transcription (STAT) proteins, and in particular STAT3,
have been established as heavily implicated in cancer. Recently, the involvement of STAT5 …