The pharmacokinetic/pharmacodynamic paradigm for antimicrobial drugs in veterinary medicine: Recent advances and critical appraisal

PL Toutain, L Pelligand, P Lees… - Journal of veterinary …, 2021 - Wiley Online Library
Abstract Pharmacokinetic/pharmacodynamic (PK/PD) modelling is the initial step in the semi‐
mechanistic approach for optimizing dosage regimens for systemically acting antimicrobial …

The potential of SERS as an AST methodology in clinical settings

O Samek, S Bernatová, F Dohnal - Nanophotonics, 2021 - degruyter.com
The ability to identify and characterize microorganisms from tiny sample volumes in a rapid
and reliable way is the first and crucial step in the diagnostics of microbial infections. Ideal …

Reasons for antimicrobial treatment failures and predictive value of in-vitro susceptibility testing in veterinary practice: An overview

A Richter, AT Feßler, A Böttner, LM Köper… - Veterinary …, 2020 - Elsevier
The choice of the most suitable antimicrobial agent for the treatment of an animal suffering
from a bacterial infection is a complex issue. The results of bacteriological diagnostics and …

Environmental perturbations during the rehabilitation of wild migratory birds induce gut microbiome alteration and antibiotic resistance acquisition

H Song, S Yi, WH Kim, JH Guk, M Ha, I Kwak… - Microbiology …, 2022 - Am Soc Microbiol
Wild migratory birds are essential for sustaining healthy ecosystems, but the effects of a
rehabilitation period on their gut microbiomes are still unclear. Here, we performed …

Nature-inspired and medicinally relevant short peptides

MG Ciulla, M Civera, S Sattin, K Kumar - Exploration of Drug Science, 2023 - air.unimi.it
Peptides constitute an important component of Nature's pharmacy and they play a significant
role in several signaling pathways acting as natural biological messengers. While nature …

Status of inhalable antimicrobial agents for lung infection: progress and prospects

SK Debnath, R Srivastava, M Debnath… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Available parenteral and oral administration of antimicrobial agents (AMAs) in
respiratory infections often show less penetration into the lung parenchyma. Due to …

Steady‐state pharmacokinetic and pharmacodynamic profiling of colistin in critically ill patients with multi‐drug–resistant gram‐negative bacterial infections, along with …

K Ram, S Sheikh, RK Bhati, CD Tripathi… - Basic & Clinical …, 2021 - Wiley Online Library
Limited data are present regarding the steady‐state pharmacokinetics and
pharmacodynamics of colistin in critically ill patients suffering from multi‐drug–resistant gram …

Antimicrobial Therapy in the Neonatal Foal

J Davis - Equine Neonatal Medicine, 2024 - Wiley Online Library
Antibiotic therapy in horses has always been challenging due to potential adverse
gastrointestinal effects and lack of approved products. Foals, in particular, present a …

Association of the origin of contamination and species of microorganisms with short‐term survival in dogs with septic peritonitis

Y Uetsu, D Houston, C Bailey… - Australian veterinary …, 2023 - Wiley Online Library
Objective To assess the association between anatomical location of contamination and
mortality in dogs with gastrointestinal and biliary origin of septic peritonitis. Methods Medical …

Comparison of the pharmacokinetics of continuous and intermittent infusions of ampicillin-sulbactam in dogs with septic peritonitis

SD Stewart, S Allen, B Eisenberg… - American Journal of …, 2023 - Am Vet Med Assoc
OBJECTIVE To evaluate the time-course of ampicillin-sulbactam and percentage of time that
its concentration is above a given MIC (T%> MIC) in dogs with septic peritonitis when …