Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
Nano-delivery systems for food bioactive compounds in cancer: Prevention, therapy, and clinical applications
IRS Vieira, CA Conte-Junior - Critical Reviews in Food Science …, 2024 - Taylor & Francis
Bioactive compounds represent a broad class of dietary metabolites derived from fruits and
vegetables, such as polyphenols, carotenoids and glucosinolates with potential for cancer …
vegetables, such as polyphenols, carotenoids and glucosinolates with potential for cancer …
Chitosan-coated nanostructured lipid carriers for transdermal delivery of tetrahydrocurcumin for breast cancer therapy
TH Truong, KP Alcantara, BPI Bulatao… - Carbohydrate …, 2022 - Elsevier
Chitosan (Ch)-coated nanostructured lipid carriers (NLCs) have great potential for
transdermal delivery with high localization of chemotherapeutics in breast cancer. This study …
transdermal delivery with high localization of chemotherapeutics in breast cancer. This study …
Nanotechnology-empowered lung cancer therapy: from EMT role in cancer metastasis to application of nanoengineered structures for modulating growth and …
Lung cancer is one of the leading causes of death in both males and females, and it is the
first causes of cancer-related deaths. Chemotherapy, surgery and radiotherapy are …
first causes of cancer-related deaths. Chemotherapy, surgery and radiotherapy are …
Recent advances in nanoformulations for quercetin delivery
EM Tomou, P Papakyriakopoulou, EM Saitani… - Pharmaceutics, 2023 - mdpi.com
Quercetin (QUE) is a flavonol that has recently received great attention from the research
community due to its important pharmacological properties. However, QUE's low solubility …
community due to its important pharmacological properties. However, QUE's low solubility …
Recent advances in boosting EGFR tyrosine kinase inhibitors-based cancer therapy
Q Pan, Y Lu, L Xie, D Wu, R Liu, W Gao… - Molecular …, 2023 - ACS Publications
Epidermal growth factor receptor (EGFR) plays a key role in signal transduction pathways
associated with cell proliferation, growth, and survival. Its overexpression and aberrant …
associated with cell proliferation, growth, and survival. Its overexpression and aberrant …
Integrating natural compounds and nanoparticle‐based drug delivery systems: A novel strategy for enhanced efficacy and selectivity in cancer therapy
Cancer remains a leading cause of death worldwide, necessitating the development of
innovative and more effective treatment strategies. Conventional cancer treatments often …
innovative and more effective treatment strategies. Conventional cancer treatments often …
Phytochemical-based nanodrugs going beyond the state-of-the-art in cancer management—Targeting cancer stem cells in the framework of predictive, preventive …
L Koklesova, J Jakubikova, D Cholujova… - Frontiers in …, 2023 - frontiersin.org
Cancer causes many deaths worldwide each year, especially due to tumor heterogeneity
leading to disease progression and treatment failure. Targeted treatment of heterogeneous …
leading to disease progression and treatment failure. Targeted treatment of heterogeneous …
Anticancer and apoptosis inducing potential of quercetin against a wide range of human malignancies
Quercetin, a flavonoid, is a dietary component that has attracted the attention of dietitians
and medicinal chemists due to its anticancer potential. It is an antioxidant that has a …
and medicinal chemists due to its anticancer potential. It is an antioxidant that has a …
Oral squamous cell carcinoma cells with acquired resistance to erlotinib are sensitive to anti-cancer effect of quercetin via pyruvate kinase M2 (PKM2)
CY Chan, SC Hong, CM Chang, YH Chen, PC Liao… - Cells, 2023 - mdpi.com
Oral squamous cell carcinoma (OSCC) frequently carries high epidermal growth factor
receptor (EGFR) expression. Erlotinib, a small molecule tyrosine kinase inhibitor (TKI), is an …
receptor (EGFR) expression. Erlotinib, a small molecule tyrosine kinase inhibitor (TKI), is an …