Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies

H Tian, T Zhang, S Qin, Z Huang, L Zhou, J Shi… - Journal of hematology & …, 2022 - Springer
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

Nano-delivery systems for food bioactive compounds in cancer: Prevention, therapy, and clinical applications

IRS Vieira, CA Conte-Junior - Critical Reviews in Food Science …, 2024 - Taylor & Francis
Bioactive compounds represent a broad class of dietary metabolites derived from fruits and
vegetables, such as polyphenols, carotenoids and glucosinolates with potential for cancer …

Chitosan-coated nanostructured lipid carriers for transdermal delivery of tetrahydrocurcumin for breast cancer therapy

TH Truong, KP Alcantara, BPI Bulatao… - Carbohydrate …, 2022 - Elsevier
Chitosan (Ch)-coated nanostructured lipid carriers (NLCs) have great potential for
transdermal delivery with high localization of chemotherapeutics in breast cancer. This study …

Nanotechnology-empowered lung cancer therapy: from EMT role in cancer metastasis to application of nanoengineered structures for modulating growth and …

HM Saleem, P Ramaiah, J Gupta, AT Jalil… - Environmental …, 2023 - Elsevier
Lung cancer is one of the leading causes of death in both males and females, and it is the
first causes of cancer-related deaths. Chemotherapy, surgery and radiotherapy are …

Recent advances in nanoformulations for quercetin delivery

EM Tomou, P Papakyriakopoulou, EM Saitani… - Pharmaceutics, 2023 - mdpi.com
Quercetin (QUE) is a flavonol that has recently received great attention from the research
community due to its important pharmacological properties. However, QUE's low solubility …

Recent advances in boosting EGFR tyrosine kinase inhibitors-based cancer therapy

Q Pan, Y Lu, L Xie, D Wu, R Liu, W Gao… - Molecular …, 2023 - ACS Publications
Epidermal growth factor receptor (EGFR) plays a key role in signal transduction pathways
associated with cell proliferation, growth, and survival. Its overexpression and aberrant …

Integrating natural compounds and nanoparticle‐based drug delivery systems: A novel strategy for enhanced efficacy and selectivity in cancer therapy

A Manzari‐Tavakoli, A Babajani, MM Tavakoli… - Cancer …, 2024 - Wiley Online Library
Cancer remains a leading cause of death worldwide, necessitating the development of
innovative and more effective treatment strategies. Conventional cancer treatments often …

Phytochemical-based nanodrugs going beyond the state-of-the-art in cancer management—Targeting cancer stem cells in the framework of predictive, preventive …

L Koklesova, J Jakubikova, D Cholujova… - Frontiers in …, 2023 - frontiersin.org
Cancer causes many deaths worldwide each year, especially due to tumor heterogeneity
leading to disease progression and treatment failure. Targeted treatment of heterogeneous …

Anticancer and apoptosis inducing potential of quercetin against a wide range of human malignancies

M Shahbaz, H Naeem, U Momal, M Imran… - … Journal of Food …, 2023 - Taylor & Francis
Quercetin, a flavonoid, is a dietary component that has attracted the attention of dietitians
and medicinal chemists due to its anticancer potential. It is an antioxidant that has a …

Oral squamous cell carcinoma cells with acquired resistance to erlotinib are sensitive to anti-cancer effect of quercetin via pyruvate kinase M2 (PKM2)

CY Chan, SC Hong, CM Chang, YH Chen, PC Liao… - Cells, 2023 - mdpi.com
Oral squamous cell carcinoma (OSCC) frequently carries high epidermal growth factor
receptor (EGFR) expression. Erlotinib, a small molecule tyrosine kinase inhibitor (TKI), is an …