[HTML][HTML] Hydroxycinnamic acids and derivatives formulations for skin damages and disorders: A review

M Contardi, M Lenzuni, F Fiorentini, M Summa… - Pharmaceutics, 2021 - mdpi.com
Alterations of skin homeostasis are widely diffused in our everyday life both due to
accidental injuries, such as wounds and burns, and physiological conditions, such as late …

[HTML][HTML] Cinnamic acid conjugates in the rescuing and repurposing of classical antimalarial drugs

AT Silva, CM Bento, AC Pena, LM Figueiredo… - Molecules, 2019 - mdpi.com
Cinnamic acids are compounds of natural origin that can be found in many different parts of
a wide panoply of plants, where they play the most diverse biological roles, often in a …

[HTML][HTML] Pyrazoles and pyrazolines as anti-inflammatory agents

M Mantzanidou, E Pontiki, D Hadjipavlou-Litina - Molecules, 2021 - mdpi.com
The five-membered heterocyclic group of pyrazoles/pyrazolines plays important role in drug
discovery. Pyrazoles and pyrazolines present a wide range of biological activities. The …

[HTML][HTML] Use of high-resolution metabolomics to assess the biological perturbations associated with maternal exposure to Bisphenol A and Bisphenol F among …

R Tchen, Y Tan, DB Barr, PB Ryan, VL Tran, Z Li… - Environment …, 2022 - Elsevier
Background Human and animal exposure to bisphenol A (BPA) has been associated with
adverse developmental and reproductive effects. The molecular mechanisms by which BPA …

[HTML][HTML] Cinnamic acid ameliorate gentamicin-induced liver dysfunctions and nephrotoxicity in rats through induction of antioxidant activities

E Babaeenezhad, N Nouryazdan, M Nasri… - Heliyon, 2021 - cell.com
This study was the first to evaluate the possible protective effects of cinnamic acid (CA)
against Gentamicin (GM) induced liver and kidney dysfunctions in rats. Adult male Wistar …

[HTML][HTML] Novel Pyrimidine Derivatives as Antioxidant and Anticancer Agents: Design, Synthesis and Molecular Modeling Studies

M Myriagkou, E Papakonstantinou, GE Deligiannidou… - Molecules, 2023 - mdpi.com
The heterocyclic ring system of pyrido [2, 3-d] pyrimidines is a privileged scaffold in
medicinal chemistry, possessing several biological activities. The synthesis of the pyrimidine …

Marine algae: A treasure trove of bioactive anti-inflammatory compounds

DS Ghallab, RS Ibrahim, MM Mohyeldin… - Marine Pollution …, 2024 - Elsevier
This comprehensive review examines the diverse classes of pharmacologically active
compounds found in marine algae and their promising anti-inflammatory effects. The review …

[HTML][HTML] Exploring the 2′-hydroxy-chalcone framework for the development of dual antioxidant and soybean lipoxygenase inhibitory agents

I Kostopoulou, A Tzani, NI Polyzos, MA Karadendrou… - Molecules, 2021 - mdpi.com
2′-hydroxy-chalcones are naturally occurring compounds with a wide array of bioactivity. In
an effort to delineate the structural features that favor antioxidant and lipoxygenase (LOX) …

[HTML][HTML] Propolis and its gastroprotective effects on nsaid-induced gastric ulcer disease: A systematic review

PA Ruiz-Hurtado, L Garduño-Siciliano… - Nutrients, 2021 - mdpi.com
Gastric ulcer disease induced by the consumption of NSAIDs is a major public health
problem. The therapy used for its treatment causes adverse effects in the patient. Propolis is …

Licofelone, a potent COX/5-LOX inhibitor and a novel option for treatment of neurological disorders

SM Razavi, D Khayatan, ZN Arab, S Momtaz… - Prostaglandins & other …, 2021 - Elsevier
Neurological disorders result in disability and morbidity. Neuroinflammation is a key factor
involved in progression or resolution of a series of neurological disorders like Huntington …