Stem cell therapy in children with traumatic brain injury

WY Lin, KH Wu, CY Chen, BC Guo, YJ Chang… - International Journal of …, 2023 - mdpi.com
Pediatric traumatic brain injury is a cause of major mortality, and resultant neurological
sequelae areassociated with long-term morbidity. Increasing studies have revealed stem …

Impact of pediatric traumatic brain injury on hippocampal neurogenesis

M Rizk, J Vu, Z Zhang - Neural Regeneration Research, 2021 - journals.lww.com
Traumatic brain injury (TBI) is a major cause of mortality and morbidity in the pediatric
population. With advances in medical care, the mortality rate of pediatric TBI has declined …

BHCNet: neural network-based brain hemorrhage classification using head CT scan

MF Mushtaq, M Shahroz, AM Aseere, H Shah… - IEEE …, 2021 - ieeexplore.ieee.org
Brain Hemorrhage is the eruption of the brain arteries due to high blood pressure or blood
clotting that could be a cause of traumatic injury or death. It is the medical emergency in …

Acute treatment with TrkB agonist LM22A-4 confers neuroprotection and preserves myelin integrity in a mouse model of pediatric traumatic brain injury

JL Fletcher, LK Dill, RJ Wood, S Wang… - Experimental …, 2021 - Elsevier
Young children have a high risk of sustaining a traumatic brain injury (TBI), which can have
debilitating life-long consequences. Importantly, the young brain shows particular …

Pediatric traumatic brain injury and abusive head trauma

M Chevignard, H Câmara-Costa… - Handbook of clinical …, 2020 - Elsevier
Childhood traumatic brain injury (TBI) commonly occurs during brain development and can
have direct, immediately observable neurologic, cognitive, and behavioral consequences …

Intranasal administration of oxytocin attenuates social recognition deficits and increases prefrontal cortex inhibitory postsynaptic currents following traumatic brain …

A Runyan, D Lengel, JW Huh, JR Barson… - Eneuro, 2021 - eneuro.org
Pediatric traumatic brain injury (TBI) results in heightened risk for social deficits that can
emerge during adolescence and adulthood. A moderate TBI in male and female rats on …

[HTML][HTML] Longitudinal fixel-based analysis reveals restoration of white matter alterations following balance training in young brain-injured patients

X Liang, CH Yeh, G Poudel, SP Swinnen… - NeuroImage: Clinical, 2021 - Elsevier
Background and objectives Traumatic brain injury (TBI) is one of the leading causes of death
and disability in children and adolescents. Young TBI patients suffer from gross motor …

Stem cell therapy for pediatric traumatic brain injury

D Lengel, C Sevilla, ZL Romm, JW Huh… - Frontiers in …, 2020 - frontiersin.org
There has been a growing interest in the potential of stem cell transplantation as therapy for
pediatric brain injuries. Studies in pre-clinical models of pediatric brain injury such as …

Reactive oxygen species-responsive HET0016 prodrug-loaded liposomes attenuate neuroinflammation and improve neurological deficit in a rat model of juvenile …

J Qin, X Chen, R Wang, Z Tian, Y Li… - Frontiers in Neuroscience, 2023 - frontiersin.org
The arachidonic acid pathway metabolite 20-hydroxyeicosatetraenoic acid (20-HETE)
contributes to ischemia/reperfusion brain injury. Inhibition of 20-HETE formation can protect …

Executive functioning, behavior, and white matter microstructure in the chronic phase after pediatric mild traumatic brain injury: results from the adolescent brain …

AK Betz, S Cetin-Karayumak, EM Bonke… - Psychological …, 2024 - cambridge.org
BackgroundMild traumatic brain injury (mTBI) is common in children. Long-term cognitive
and behavioral outcomes as well as underlying structural brain alterations following …