Background Side effects of oral contraceptive (OC) pills discourage adherence to and
continuation of OC regimens. Strategies to decrease adverse effects led to the introduction …

Objective: To review and compare the newer progestins desogestrel, norgestimate, and
gestodene with regard to chemistry, pharmacokinetics, efficacy, and tolerability. Data …

Control of spotting and breakthrough bleeding and absence of withdrawal bleeding,
collectively termed cycle control, is the single most important determinant of whether a new …

Spotting and bleeding are among the most common side effects associated with oral
contraceptive (OC) use and their occurrence is a prime determinant of whether a new user …

Objective: To review and compare the risk-benefit profile of triphasic oral contraceptives with
that of low-dose monophasic oral contraceptives. Design: Literature on currently marketed …

The effects of a 24-day regimen containing 15 μg ethinyl estradiol (EE) plus 60 μg
gestodene on cycle control and on hemostasis, were evaluated in 58 healthy women (age …

Objective To investigate the efficacy, cycle control and tolerability of a phasic oral
contraceptive containing ethinylestradiol 35/30/30 μg and desogestrel 50/100/150 μg …

Gestodene, one of three new gonane progestins, is the most potent on a per weight basis in
regard to progestational effects and has little or no estrogenic effect. In in vivo animal …

The clinical and metabolic effects of a low-dose triphasic oral contraceptive containing
gestodene were investigated in 42 healthy women during 6 months of treatment. No …

This prospective, multicenter study was conducted to evaluate the contraceptive reliability,
cycle control and tolerability of a 21-day oral contraceptive regimen containing 20 μg …