[HTML][HTML] Extracellular vesicles and their potential significance in the pathogenesis and treatment of osteoarthritis

AM Mustonen, P Nieminen - Pharmaceuticals, 2021 - mdpi.com
Osteoarthritis (OA) is a chronic joint disease characterized by inflammation, gradual
destruction of articular cartilage, joint pain, and functional limitations that eventually lead to …

[HTML][HTML] Metformin attenuates symptoms of osteoarthritis: role of genetic diversity of Bcl2 and CXCL16 in OA

N Alimoradi, M Tahami, N Firouzabadi, E Haem… - Arthritis Research & …, 2023 - Springer
Objective This study aimed to evaluate the effectiveness of metformin versus placebo in
overweight patients with knee osteoarthritis (OA). In addition, to assess the effects of …

Diet and lifestyle modifications: An update on non‐pharmacological approach in the management of osteoarthritis

A Shahid, M Inam‐Ur‐Raheem… - Journal of Food …, 2022 - Wiley Online Library
Osteoarthritis (OA) is a degenerative joint disease, a leading cause of bone‐related
disabilities affecting the quality of life of a huge segment of the global population. To …

Development and characterization of carbohydrate-based thermosensitive hydrogels for cartilage tissue engineering

CB Westin, MHT Nagahara, MC Decarli, DJ Kelly… - European Polymer …, 2020 - Elsevier
In this work, thermosensitive hydrogels formulated with methylcellulose, xanthan gum and/or
carboxymethyl chitosan were developed and characterized as a potential treatment for …

The effect of local heat therapy versus cold rub gel on pain and joint functions in patients with knee osteoarthritis

M Ariana, A Afrasiabifar… - Clinical Nursing …, 2022 - journals.sagepub.com
This study compared the effect of local heat therapy versus cold rub gel on pain and joint
function in patients with knee osteoarthritis. One hundred seventeen patients with knee …

[HTML][HTML] Neuropathic pain in primary knee osteoarthritis patients: correlation with physical function, quality of life, disease severity, and serum beta nerve growth factor …

SR Kamel, RS Ibrahim, HM Moens… - Egyptian Rheumatology …, 2021 - Springer
Background Neuropathic mechanisms are thought to play a role in knee osteoarthritis (KOA)
pain. Neuropathic pain questionnaires can promote diagnosis of a neuropathic component …

[HTML][HTML] Coniferaldehyde prevents articular cartilage destruction in a murine model via Nrf2/HO‑1 pathway

D Cai, J Wang, S Chen, L Jiang… - Molecular …, 2021 - spandidos-publications.com
Osteoarthritis (OA) is the most prevalent joint disorder characterized by progressive cartilage
damage, resulting in gradual disability among the elderly. We previously provided in vivo …

[HTML][HTML] Treatment of grade III knee osteoarthritis with bone marrow stimulation and intraarticular injection of triamcinolone and hyaluronic acid combination; three …

A Arief, MA Usman, M Sakti, AMT Lubis… - International Journal of …, 2022 - Elsevier
Introduction and importance Osteoarthritis is a severe joint disease that affects more than
60% of the elderly and more common an idiopathic disease or unknown cause although …

[HTML][HTML] Manual therapy versus closed kinematic exercises—the influence on the range of movement in patients with knee osteoarthritis: a pilot study

K Hejdysz, J Goślińska, A Wareńczak, J Dudzińska… - Applied sciences, 2020 - mdpi.com
Reduced range of motion is one of the main symptoms of knee osteoarthritis. These deficits
are believed to have a negative impact on activities of daily living. The aim of the study was …

A Novel Target Strategy for the Treatment of Arthritis

PA Mandal, NN Dhoble, P Dhapke… - Asian Journal of …, 2024 - search.proquest.com
arthritis is typically thought either acute or chronic inflammation which causes pain in the
affected joint along with structural damage. According to some views, the innate immune …