[HTML][HTML] Multifactorial mechanism of sarcopenia and sarcopenic obesity. Role of physical exercise, microbiota and myokines

J Bilski, P Pierzchalski, M Szczepanik, J Bonior… - Cells, 2022 - mdpi.com
Obesity and ageing place a tremendous strain on the global healthcare system. Age-related
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …

[HTML][HTML] Health consequences of sarcopenic obesity: a narrative review

E Roh, KM Choi - Frontiers in endocrinology, 2020 - frontiersin.org
Sarcopenia is defined as the age-related loss of muscle mass and strength or physical
performance. Increased amounts of adipose tissue often accompany sarcopenia, a condition …

Sarcopenic obesity or obese sarcopenia: a cross talk between age-associated adipose tissue and skeletal muscle inflammation as a main mechanism of the …

A Kalinkovich, G Livshits - Ageing research reviews, 2017 - Elsevier
Sarcopenia, an age-associated decline in skeletal muscle mass coupled with functional
deterioration, may be exacerbated by obesity leading to higher disability, frailty, morbidity …

[HTML][HTML] Strategies to prevent sarcopenia in the aging process: role of protein intake and exercise

PS Rogeri, R Zanella Jr, GL Martins, MDA Garcia… - Nutrients, 2021 - mdpi.com
Sarcopenia is one of the main issues associated with the process of aging. Characterized by
muscle mass loss, it is triggered by several conditions, including sedentary habits and …

[HTML][HTML] Obesity, metabolic syndrome, and musculoskeletal disease: common inflammatory pathways suggest a central role for loss of muscle integrity

KH Collins, W Herzog, GZ MacDonald… - Frontiers in …, 2018 - frontiersin.org
Inflammation can arise in response to a variety of stimuli, including infectious agents, tissue
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve …

[HTML][HTML] The impact of obesity on skeletal muscle strength and structure through adolescence to old age

DJ Tomlinson, RM Erskine, CI Morse, K Winwood… - Biogerontology, 2016 - Springer
Obesity is associated with functional limitations in muscle performance and increased
likelihood of developing a functional disability such as mobility, strength, postural and …

An overview of murine high fat diet as a model for type 2 diabetes mellitus

A Heydemann - Journal of diabetes research, 2016 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) is a worldwide epidemic, which by all predictions will only
increase. To help in combating the devastating array of phenotypes associated with T2DM a …

[HTML][HTML] The role of macrophages in osteoarthritis and cartilage repair

CL Wu, NS Harasymowicz, MA Klimak… - Osteoarthritis and …, 2020 - Elsevier
Osteoarthritis (OA) is a family of degenerative diseases affecting multiple joint tissues.
Despite the diverse etiology and pathogenesis of OA, increasing evidence suggests that …

[HTML][HTML] Advances in understanding of the role of lipid metabolism in aging

KW Chung - Cells, 2021 - mdpi.com
During aging, body adiposity increases with changes in the metabolism of lipids and their
metabolite levels. Considering lipid metabolism, excess adiposity with increased lipotoxicity …

[HTML][HTML] Reference values for skeletal muscle mass–current concepts and methodological considerations

CO Walowski, W Braun, MJ Maisch, B Jensen, S Peine… - Nutrients, 2020 - mdpi.com
Assessment of a low skeletal muscle mass (SM) is important for diagnosis of ageing and
disease-associated sarcopenia and is hindered by heterogeneous methods and …