Obesity is a growing health problem in both children and adults, impairing physical and
mental state and impacting health care system costs in both developed and developing …

The plasminogen system is a critical proteolytic system responsible for the remodeling of the
extracellular matrix (ECM). The master regulator of the plasminogen system, plasminogen …

Physical activity and diet are essential for maintaining good health and preventing the
development of non-communicable diseases, especially in the older adults. One aspect that …

Obesity and osteoporosis are two alarming health disorders prominent among middle and
old age populations, and the numbers of those affected by these two disorders are …

Skeletal muscle plays important roles in whole-body energy homeostasis. Excessive
skeletal muscle lipid accumulation is associated with some metabolic diseases such as …

The loss of skeletal muscle mass is observed in many pathophysiological conditions,
including aging and obesity. The loss of muscle mass and function with aging is defined as …

Skeletal muscle is a large organ that accounts for up to half the total mass of the human
body. A progressive decline in muscle mass and strength occurs with ageing and in some …

Due to its essential role in movement, insulating the internal organs, generating heat to
maintain core body temperature, and acting as a major energy storage depot, any …

Skeletal muscle utilizes both free fatty acids (FFAs) and glucose that circulate in the blood
stream. When blood glucose levels acutely increase, insulin stimulates muscle glucose …

Obesity causes progressive lipid accumulation and insulin resistance within muscle cells
and affects skeletal muscle fibres and muscle mass that demonstrates atrophy and …