[HTML][HTML] Emerging role of GLP-1 agonists in obesity: a comprehensive review of randomised controlled trials

MS Popoviciu, L Păduraru, G Yahya… - International journal of …, 2023 - mdpi.com
Obesity is a chronic disease with high prevalence and associated comorbidities, making it a
growing global concern. These comorbidities include type 2 diabetes, hypertension …

Semaglutide and cancer: A systematic review and meta-analysis

L Nagendra, BG Harish, M Sharma, D Dutta - Diabetes & Metabolic …, 2023 - Elsevier
Background French national health care insurance system database has suggested 1–3
years use of glucagon like peptide-1 receptor agonists (GLP1RA)(exenatide, liraglutide and …

Metabolically healthy obesity: are interventions useful?

BJ Mathis, K Tanaka, Y Hiramatsu - Current Obesity Reports, 2023 - Springer
Abstract Purpose of Review This review aims to detail the current global research state of
metabolically healthy obesogenesis with regard to metabolic factors, disease prevalence …

Cost-effectiveness of endoscopic, surgical and pharmacological obesity therapies: a microsimulation and threshold analyses

M Saumoy, D Gandhi, S Buller, S Patel, Y Schneider… - Gut, 2023 - gut.bmj.com
Objective Weight loss interventions to treat obesity include sleeve gastrectomy (SG), lifestyle
intervention (LI), endoscopic sleeve gastroplasty (ESG) and semaglutide. We aimed to …

Semaglutide 2.4 Mg for the management of overweight and obesity: systematic literature review and meta-analysis

I Smith, E Hardy, S Mitchell, S Batson - … , Metabolic Syndrome and …, 2022 - Taylor & Francis
Purpose Semaglutide has demonstrated safe and effective weight loss for overweight and
obesity, including participants with concomitant type 2 diabetes mellitus (T2DM), in …

Efficacy and safety of semaglutide in patients with heart failure with preserved ejection fraction and obesity

A Rehman, S Saidullah, M Asad, UR Gondal… - Clinical …, 2024 - Wiley Online Library
Background Semaglutide, a once‐weekly glucagon‐like peptide‐1 receptor agonist, has
shown promise in weight management and cardiovascular outcomes in other populations …

Management of type 2 diabetes, obesity, or nonalcoholic steatohepatitis with high‐dose GLP‐1 receptor agonists and GLP‐1 receptor‐based co‐agonists

RM Goldenberg, JD Gilbert, P Manjoo… - Obesity …, 2024 - Wiley Online Library
Summary Type 2 diabetes (T2D), obesity, and nonalcoholic fatty liver disease/nonalacoholic
steatohepatitis (NAFLD/NASH) share mutual causalities. Medications that may offer clinical …

Female obesity: clinical and psychological assessment toward the best treatment

V Guglielmi, R Dalle Grave, F Leonetti… - Frontiers in …, 2024 - frontiersin.org
Obesity is a heterogeneous condition which results from complex interactions among
sex/gender, sociocultural, environmental, and biological factors. Obesity is more prevalent in …

Obesity management for the hepatologist–what to do, how to do it and why

KD Watt, S Paul, MQ Khan, M Siddiqui, J Lam… - Hepatology, 2023 - journals.lww.com
Obesity is highly prevalent in hepatology clinics and has significant impact in chronic liver
disease and patient management. Hepatologists and gastroenterologist need to be actively …

[HTML][HTML] Semaglutide as a Possible Calmodulin Binder: Ligand-Based Computational Analyses and Relevance to Its Associated Reward and Appetitive Behaviour …

G Floresta, D Arillotta, V Catalani… - Scientia …, 2024 - mdpi.com
Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has gained considerable
attention as a therapeutic agent for type 2 diabetes mellitus and obesity. Despite its clinical …