Conjunctival epithelial and goblet cell function in chronic inflammation and ocular allergic inflammation

DA Dartt, S Masli - Current opinion in allergy and clinical …, 2014 - journals.lww.com
Conjunctival epithelial and goblet cell function in chronic... : Current Opinion in Allergy and
Clinical Immunology Conjunctival epithelial and goblet cell function in chronic inflammation and …

Membrane-associated mucins of the ocular surface: New genes, new protein functions and new biological roles in human and mouse

ME Fini, S Jeong, H Gong, R Martinez-Carrasco… - Progress in retinal and …, 2020 - Elsevier
The mucosal glycocalyx of the ocular surface constitutes the point of interaction between the
tear film and the apical epithelial cells. Membrane-associated mucins (MAMs) are the …

Ocular mucosal immunity

NL O'Sullivan, PC Montgomery - Mucosal immunology, 2015 - Elsevier
Mucosal immunity defends the ocular surface against antigenic challenge and microbial
invasion. The principal effector site is the lacrimal gland, where immunoglobulin A (IgA) …

[HTML][HTML] Conjunctival intraepithelial lymphocytes, lacrimal cytokines and ocular commensal microbiota: analysis of the three main players in allergic conjunctivitis

JC Zarzuela, R Reinoso, A Armentia… - Frontiers in …, 2022 - frontiersin.org
Conjunctival intraepithelial lymphocytes, tear soluble molecules and commensal microbiota
have important roles in the ocular mucosal immune response in healthy and diseased …

[HTML][HTML] Immunomodulatory cross-talk between conjunctival goblet cells and dendritic cells

L Contreras-Ruiz, S Masli - PloS one, 2015 - journals.plos.org
Goblet cells are secretory epithelial cells of mucosal tissues that confer protection from
environmental agents or pathogens via expression and secretion of soluble mucins. Loss of …

[HTML][HTML] Single-cell landscape reveals the epithelial cell-centric pro-inflammatory immune microenvironment in dry eye development

Z Liu, H Xie, L Li, D Jiang, Y Qian, X Zhu, M Dai, Y Li… - Mucosal …, 2023 - Elsevier
Dry eye disease (DED) is a prevalent chronic eye disease characterized by an aberrant
inflammatory response in ocular surface mucosa. The immunological alterations underlying …

[HTML][HTML] Severity of Sjögren's syndrome keratoconjunctivitis sicca increases with increased percentage of conjunctival antigen-presenting cells

SC Pflugfelder, F Bian, K Gumus, W Farley… - International journal of …, 2018 - mdpi.com
This study investigated the relationship between clinical severity and percentage of
conjunctival antigen-presenting cells (APCs) in Sjögren's syndrome (SS)-associated …

[HTML][HTML] Conjunctiva resident γδ T cells expressed high level of IL-17A and promoted the severity of dry eye

L Li, Y Li, X Zhu, B Wu, Z Tang, H Wen… - … & Visual Science, 2022 - iovs.arvojournals.org
Purpose: Conjunctival inflammation promotes ocular surface disorders in dry eye disease
(DED). Here we identified γδ T cells as the predominant source of IL-17A in the murine …

[HTML][HTML] Delivery of a chlamydial adhesin N-PmpC subunit vaccine to the ocular mucosa using particulate carriers

A Inic-Kanada, M Stojanovic, S Schlacher, E Stein… - PloS one, 2015 - journals.plos.org
Trachoma, caused by the intracellular bacterium Chlamydia trachomatis (Ct), remains the
world's leading preventable infectious cause of blindness. Recent attempts to develop …

The transconjunctival orbitotomy: A versatile approach to the orbit and beyond

I Mombaerts, RC Allen - Survey of Ophthalmology, 2023 - Elsevier
In the management of orbital disorders and defects, minimally invasive surgical approaches
have become increasingly efficient for their reduction of operative trauma and access …