[HTML][HTML] Improving cancer immunotherapy by preventing cancer stem cell and immune cell linking in the tumor microenvironment

D Li, L Wang, B Jiang, Y Jing, X Li - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Cancer stem cells are the key link between malignant tumor progression and drug
resistance. This cell population has special properties that are different from those of …

Triggering receptor expressed in myeloid cells 1 (TREM1) as a potential prognostic biomarker and association with immune infiltration in oral squamous cell …

B Kannan, C Pandi, A Pandi, VP Jayaseelan… - Archives of Oral …, 2024 - Elsevier
Objective The objective of this study is to investigate the significance and impact of
Triggering Receptor Expression on Myeloid Cells-1 (TREM-1) in the context of oral …

[HTML][HTML] MDSCs-derived GPR84 induces CD8+ T-cell senescence via p53 activation to suppress the antitumor response

J Liu, J Liu, G Qin, J Li, Z Fu, J Li, M Li… - … for Immunotherapy of …, 2023 - ncbi.nlm.nih.gov
Methods The role and underlying mechanism that MDSCs or exosomes (Exo) regulates the
function of CD8+ T cells were investigated using immunofluorescence, fluorescence …

[HTML][HTML] TREM1: activation, signaling, cancer and therapy

C Li, C Cai, D Xu, X Chen, J Song - Pharmacological Research, 2024 - Elsevier
Triggering receptor expressed on myeloid cells 1 (TREM1) is a cell surface receptor
expressed on neutrophils, monocytes and some tissue macrophages, where it functions as …

[HTML][HTML] Immune Cell Migration to Cancer

AT Ryan, M Kim, K Lim - Cells, 2024 - mdpi.com
Immune cell migration is required for the development of an effective and robust immune
response. This elegant process is regulated by both cellular and environmental factors, with …

Pharmacological Inhibition or Silencing of TREM1 Restrains HCC Cell Metastasis by Inactivating TLR/PI3K/AKT Signaling

L Ren, G Qiao, S Zhang, Z Zhang, S Lv - Cell Biochemistry and Biophysics, 2024 - Springer
Hepatocellular carcinoma (HCC), a widely prevalent malignancy strongly linked to
inflammation, remains a significant public health concern. Triggering receptor expressed on …

Sex differences in glioblastoma based on tumor subtypes

B Segura-Collar, R Gargini - Neuro-Oncology, 2024 - academic.oup.com
1/2 (IDH1/2) wild type (wt) based on inflammatory processes, suggesting that the
inflammation defined in our work linked to the infiltration of myeloid-derived suppressor cells …