Recently, in silico techniques have gained tremendous popularity in the field of small
molecule drug discovery. The computational jobs include not only hit generation, lead …

Cancer, which is the uncontrolled growth of cells, is the second leading cause of death after
heart disease. Targeting drugs, especially to specific genes and proteins involved in growth …

Pyrazolines are a significant class of heterocyclic compounds with essential biological
activities. They are quite stable, which has inspired medicinal chemists to experiment with …

In the present work, a concise library of benzothiazole-derived pyrazoline-based thiazole (1–
17) was designed and synthesized by employing a multistep reaction strategy. The newly …

In the present investigation, derivatives from (2–6) containing pyrimidine-2-thione moiety
incorporated with different heterocycles such as pyrazoline, phenyl pyrazoline, and …

In this study, three different chalcone compounds were synthesized by Aldol condensation
reaction. 4-hydroxybenzaldehyde and ketone compounds (acetophenone, acetofuran and …

Thiazole‐pyrazoline Schiff base hybrids have a broad range of pharmacological potential
with an ability to control the activity of numerous metabolic enzymes. In this work, a greener …

Chalcones are members of the flavonoid family and act as intermediates in the biosynthesis
of flavonoids, which are widespread in plants. Meanwhile, chalcones are important …

In this study, the anticancer activity of umbelliferone (7-hydroxycoumarin-UMB) was
investigated in MKN-45 human gastric cancer and MIA PaCa-2 human pancreatic cancer …

Novel pyrazoline derivatives containing benzo [d] thiazol‐2 (3H)‐one moiety were
synthesized and screened for their inhibitory properties against urease, a clinically important …