Alzheimer's disease (AD) is the most common cause of dementia worldwide. The etiology is
multifactorial, and pathophysiology of the disease is complex. Data indicate an exponential …

The serotonergic pathways originating in the dorsal and median raphe nuclei (DR and MnR,
respectively) are critically involved in cortical function. Serotonin (5-HT), acting on …

Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterized by the
loss of memory, multiple cognitive impairments and changes in the personality and …

Symptoms of cognitive dysfunction like memory loss, poor concentration, impaired learning
and executive functions are characteristic features of both schizophrenia and Alzheimer's …

The neurotransmitter dopamine (DA) has a long association with normal functions such as
motor control, cognition, and reward, as well as a number of syndromes including drug …

Since their discovery in the mammalian brain, it has been apparent that serotonin (5-HT)
and dopamine (DA) interactions play a key role in normal and abnormal behavior …

The serotonergic system is implicated in the neurobiological control of learning and memory,
both in healthy individuals and pathological disorders, although the underlying mechanisms …

The hippocampus plays an important role in emotional and cognitive processing, and both
of these domains are affected in patients with major depressive disorder (MDD). Extensive …

Serotonergic antidepressant drugs have been commonly used to treat mood and anxiety
disorders, and increasing evidence suggests potential use of these drugs beyond current …

Abstract Serotonin (5-hydroxytrympamine or 5-HT) is one of the phylogenetically oldest
neurotransmitters, and the serotonergic system is among the earliest developed neuronal …