Objectives To review and update the evidence on predictors of poor outcome (death,
persistent vegetative state or severe neurological disability) in adult comatose survivors of …

Traumatic brain injury (TBI) is acquired from an external force, which can inflict devastating
effects to the brain vasculature and neighboring neuronal cells. Disruption of vasculature is …

Despite advances in resting state functional magnetic resonance imaging investigations,
clinicians remain with the challenge of how to implement this paradigm on an individualized …

Background Prediction of neurological outcome after cardiac arrest is a major challenge.
The aim of this study was to assess whether quantitative whole-brain white matter fractional …

Importance Evidence from preclinical models indicates that xenon gas can prevent the
development of cerebral damage after acute global hypoxic-ischemic brain injury but, thus …

Introduction Hypoxic-ischemic brain injury is the main cause of death and disability of
comatose patients after cardiac arrest. Early and reliable prognostication is challenging …

Neurological examination of non-communicating patients relies on a few decisive items that
enable the crucial distinction between vegetative state (VS)—also coined unresponsive …

Consciousness loss in patients with severe brain injuries is associated with reduced
functional connectivity of the default mode network (DMN), fronto-parietal network, and …

Objective The relationship between residual brain tissue in patients with disorders of
consciousness (DOC) and the clinical condition is unclear. This observational study aimed …

Purpose To assess whether early brain functional connectivity is associated with functional
recovery 1 year after cardiac arrest (CA). Materials and Methods Enrolled in this prospective …