[HTML][HTML] Drug repurposing to enhance antitumor response to PD-1/PD-L1 immune checkpoint inhibitors

X Thuru, R Magnez, H El-Bouazzati, G Vergoten… - Cancers, 2022 - mdpi.com
Simple Summary Novel pharmacological approaches are needed to improve treatments of
advanced cancers, despite the considerable benefit of immunotherapy. New drugs are …

[HTML][HTML] Thyroid and Heart: A Fatal Pathophysiological Attraction in a Controversial Clinical Liaison

A Pingitore, F Mastorci, MFL Lazzeri, C Vassalle - Endocrines, 2023 - mdpi.com
The thyroid–heart relationship has a long and articulated history of its own, a history that
encompasses physiological and pathophysiological knowledge. In recent years, molecular …

Effects of Triiodothyronine Treatment in an Animal Model of Heart Failure with Preserved Ejection Fraction

JS Neves, AR Leite, G Conceição, A Gonçalves… - Thyroid, 2023 - liebertpub.com
Background: Low levels of triiodothyronine (T3) are common in patients with heart failure
(HF). Our aim was to evaluate the effects of supplementation with low and replacement …

Indications for Intravenous T3 and T4

JD Feldkamp, J Feldkamp - Hormone and Metabolic Research, 2024 - thieme-connect.com
Therapy with thyroid hormones normally is restricted to substitution therapy of patients with
primary or secondary hypothyroidism. Typically, thyroid hormones are given orally. There …

Cardiac Safety and Efficacy of Combination Levothyroxine and L-Triiodothyronine in Patients with Athyreotic Hypothyroidism: Reassuring Initial Data but More Is …

S Razvi - Thyroid, 2023 - liebertpub.com
Thyroid hormones (TH) play an important role in regulating the development and function of
almost all tissues including the cardiovascular system (1). Levothyroxine (LT4), a synthetic L …

Triiodothyronine Supplementation for Children Undergoing Cardiopulmonary Bypass: A Meta-Analysis

MR Radman, AE Slee, EM Marwali, MA Portman - Pediatric Cardiology, 2024 - Springer
Specific pediatric populations have exhibited disparate responses to triiodothyronine (T3)
repletion during and after cardiopulmonary bypass (CPB). Objective: To determine if T3 …

Inotropes

SK Motwani, H Saunders - Anaesthesia & Intensive Care Medicine, 2024 - Elsevier
Inotropes are a group of drugs that alter myocardial contractility by increasing intracellular
calcium or enhancing sensitivity to it. However, they may result in suboptimal myocardial …

New‐onset postoperative atrial fibrillation after coronary artery bypass graft surgery

M Engin, U Aydın, G Cebeci… - Polish Heart Journal …, 2022 - journals.viamedica.pl
We have read with great interest the article by Smukowska-Gorynia et al.[1], entitled
“Neopterin as a predictive biomarker of postoperative atrial fibrillation following coronary …

Perioperative vitamin support therapy to prevent postoperative atrial fibrillation

M Engin, O Guvenc, AK As, AF Ozyazicioglu - General Thoracic and …, 2024 - Springer
Dear editor, We read with interest the paper by Alirezai et al.[1] entitled “Effect of
preoperative vitamin D on postoperative atrial fibrillation incidence after coronary artery …

Preliminary Experience of Early T3 Therapy in Patients with Acute Myocardial Infarction

TS Thompson, NS Ospina - Clinical Thyroidology, 2022 - liebertpub.com
Background There is a strong association between thyroid hormones and cardiac function,
as supported by physiologic and clinical observational evidence, in both healthy and …