ZD6474 Attenuates Fibrosis and Inhibits Neovascularization in Human Pterygium by Suppressing AKT-mTOR Signaling Pathway

W Liu, T Lin, L Gong - Journal of Ocular Pharmacology and …, 2023 - liebertpub.com
Purpose: To investigate the antifibrotic effect of ZD6474 in human pterygium fibroblasts
(HPFs) and angiogenesis in human umbilical vein endothelial cells (HUVECs) compared …

[HTML][HTML] ZD6474 attenuates TGF-β1-induced fibrosis in human Tenon fibroblasts and inhibits neovascularization via AKT-mTOR signaling pathway

W Liu, Y Chen, X Song, Y Xue, Y Zhang - International Ophthalmology, 2023 - Springer
Purpose To investigate the anti-fibrotic effect of ZD6474 (a novel inhibitor of VEGF and EGF)
in TGF-β1 stimulated human Tenon's capsule fibroblasts (HTFs) and the anti-angiogenetic …