[HTML][HTML] Reducing neuroinflammation via therapeutic compounds and lifestyle to prevent or delay progression of Parkinson's disease

E Kip, LC Parr-Brownlie - Ageing Research Reviews, 2022 - Elsevier
Parkinson's disease (PD) is the second most common age-associated neurodegenerative
disorder and is characterised by progressive loss of dopamine neurons in the substantia …

Roles of the miR-155 in neuroinflammation and neurological disorders: a potent biological and therapeutic target

SH Rastegar-Moghaddam… - Cellular and molecular …, 2023 - Springer
Neuroinflammation plays a crucial role in the development and progression of neurological
disorders. MicroRNA-155 (miR-155), a miR is known to play in inflammatory responses, is …

MicroRNA-22: A novel and potent biological therapeutics in neurological disorders

SH Rastegar-Moghaddam… - Molecular …, 2022 - Springer
MicroRNAs (miRs) are regulatory RNAs with 18–25 nucleotides lengths involved in various
biological processes. Some miRs, including miR-22, play an essential role in regulating …

Combining NGN2 programming and dopaminergic patterning for a rapid and efficient generation of hiPSC-derived midbrain neurons

R Sheta, M Teixeira, W Idi, M Pierre… - Scientific Reports, 2022 - nature.com
The use of human derived induced pluripotent stem cells (hiPSCs) differentiated to
dopaminergic (DA) neurons offers a valuable experimental model to decorticate the cellular …

Antitumor Effects of Natural Compounds Derived from Allium sativum on Neuroblastoma: An Overview

CC Patiño-Morales, R Jaime-Cruz, C Sánchez-Gómez… - Antioxidants, 2021 - mdpi.com
Garlic (Allium sativum) has been used in alternative medicine to treat several diseases, such
as cardiovascular and neurodegenerative diseases, cancer, and hepatic diseases. Several …

Oral administration of Limonin (LM) exerts neuroprotective effects by inhibiting neuron autophagy and microglial activation in 6-OHDA-injected rats

X Gao, D He, Y Liu, M Cui, Z Li, J Li, Y He… - International …, 2023 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder that occurs most frequently in
middle-aged and elderly people. It is characterized by an insidious onset and a complex …

Bio-synthesized selenium nanoparticles ameliorate Brain oxidative stress in Parkinson disease rat models

S Salaramoli, H Amiri, HR Joshaghani… - Metabolic Brain …, 2023 - Springer
Aim Parkinson disease (PD) is a prevalent central nervous system degenerative condition
that impacts elderly people. Recent clinical and experimental study findings have …

The Pharmacological Activity of Garlic (Allium sativum) in Parkinson's Disease: From Molecular Mechanisms to the Therapeutic Potential

D Rakshit, S Nayak, S Kundu… - ACS Chemical …, 2023 - ACS Publications
Parkinson's disease (PD), one of the most common neurological diseases worldwide, is
mainly characterized neuropathologically by the dopaminergic neurodegeneration in the …

Optimization of the black garlic processing method and development of black garlic jam using high-pressure processing

WC Chang, WC Lin, SC Wu - Foods, 2023 - mdpi.com
Black garlic has many beneficial effects, and it has a less spicy flavor. However, its aging
conditions and related products still need to be further investigated. The present study aims …

Effects of vitamin D (VD3) supplementation on the brain mitochondrial function of male rats, in the 6-OHDA-induced model of Parkinson's disease

LA de Lima, PLO Cunha, IBF Calou, KRT Neves… - Neurochemistry …, 2022 - Elsevier
Mitochondria dysfunction is an important factor involved in PD pathogenesis. We reported
neuroprotective actions of vitamin D (VD3) on a PD model, and now we investigated the …