Sex and gender differences in kidney cancer: clinical and experimental evidence

AJ Peired, R Campi, ML Angelotti, G Antonelli, C Conte… - Cancers, 2021 - mdpi.com
Simple Summary Kidney cancer is a frequent malignant tumor that accounts for
approximately 5% of all cancer incidences. It affects both males and females, but males are …

A genetic basis for sex differences in Xp11 translocation renal cell carcinoma

M Achom, A Sadagopan, C Bao, F McBride, J Li… - Cell, 2024 - cell.com
Xp11 translocation renal cell carcinoma (tRCC) is a rare, female-predominant cancer driven
by a fusion between the transcription factor binding to IGHM enhancer 3 (TFE3) gene on …

Renal neoplasms in young adults

P Gopee-Ramanan, S Chin, C Lim, KP Shanbhogue… - Radiographics, 2022 - pubs.rsna.org
Renal cell carcinoma (RCC) is usually diagnosed in older adults (the median age of
diagnosis is 64 years). Although less common in patients younger than 45 years, RCCs in …

[HTML][HTML] A genetic basis for cancer sex differences revealed in Xp11 translocation renal cell carcinoma

M Achom, A Sadagopan, C Bao, F McBride, Q Xu… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Xp11 translocation renal cell carcinoma (tRCC) is a female-predominant kidney cancer
driven by translocations between the TFE3 gene on chromosome Xp11. 2 and partner …

Clinicopathologic, treatment and prognosis study of 46 Xp11. 2 translocation/TFE3 gene fusion renal cell carcinomas

J Zhou, L Zhao, Z Yang, Y Chen, X Wu, W Xue - BMC urology, 2022 - Springer
Purpose To report the clinicopathological features and mid-to long-term oncologic results of
Xp11. 2 translocation/transcription factor E3 (TFE3) gene fusion renal cell carcinomas …

Renal cell carcinoma associated with Xp11. 2 translocation/transcription factor E3 gene fusion: A case report and literature review

D Yang, W Tang, M Liu, Z Xie, F Shi… - Oncology …, 2023 - spandidos-publications.com
Renal cell carcinoma (RCC) associated with Xp11. 2 translocation/transcription factor E3
(TFE3) gene fusion is a rare subtype of RCC. A 31-year-old male patient was admitted to …

Estrogen associates with female predominance in Xp11. 2 translocation renal cell carcinoma

Y Lu, Y Zhu, W Ma, N Liu, X Dong, Q Shi, F Yu… - Scientific Reports, 2023 - nature.com
Based on the epidemiological characteristics of susceptibility and age selectivity for women
in Xp11. 2 translocation renal cell carcinoma (Xp11. 2 tRCC), we inferred that estrogen was …

Contrast‐Enhanced Ultrasound Features of Adult Xp11. 2 Translocation Renal Cell Carcinoma: Differential Diagnosis With Three Main Renal Cell Carcinoma …

W Ma, F Zhang, H Huang, W Wang… - … of Ultrasound in …, 2022 - Wiley Online Library
Objectives To investigate the sonographic features in Xp11. 2 translocation renal cell
carcinoma (Xp11. 2 tRCC) using both conventional ultrasound (US) and contrast‐enhanced …

Estradiol increases risk of topoisomerase IIβ-mediated DNA strand breaks to initiate Xp11. 2 translocation renal cell carcinoma

Q Shi, N Liu, L Yang, Y Chen, Y Lu, H Guo… - Cell Communication and …, 2021 - Springer
Background Xp11. 2 translocation renal cell carcinoma (tRCC) is defined by translocation of
the transcription factor E3 (TFE3) gene located on chromosome Xp11. 2. Due to the high …

MED15-TFE3 Renal Cell Carcinoma: a Xp11 Translocation Renal Cell Carcinoma Subtype With Distinct Clinicopathological Features and Superior Prognosis

W Gan, X Dong, W Guo, P Zhou, J Pan, H Guo - 2022 - researchsquare.com
Background: MED15-TFE3 renal cell carcinoma is a rare subtype of the Xp11 translocation
renal cell carcinoma. To data, only 14 cases of MED15-TFE3 renal cell carcinoma have …