Matrix metalloproteinase: An upcoming therapeutic approach for idiopathic pulmonary fibrosis

S Mahalanobish, S Saha, S Dutta, PC Sil - Pharmacological Research, 2020 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a debilitating condition where excess collagen
deposition occurs in the extracellular matrix. At first sight, it is expected that the level of …

Nutrition in patients with idiopathic pulmonary fibrosis: critical issues analysis and future research directions

P Faverio, M Bocchino, A Caminati, A Fumagalli… - Nutrients, 2020 - mdpi.com
In idiopathic pulmonary fibrosis (IPF), several factors may have a negative impact on the
nutritional status, including an increased respiratory muscles load, release of inflammation …

Biochanin-A ameliorates pulmonary fibrosis by suppressing the TGF-β mediated EMT, myofibroblasts differentiation and collagen deposition in in vitro and in vivo …

SB Andugulapati, K Gourishetti, SK Tirunavalli… - Phytomedicine, 2020 - Elsevier
Abstract Background: Idiopathic Pulmonary Fibrosis (IPF) is a progressive inflammatory
disorder driven by a fibrotic cascade of events such as epithelial to mesenchymal transition …

Geriatric Nutritional Risk Index is a predictor of tolerability of antifibrotic therapy and mortality risk in patients with idiopathic pulmonary fibrosis

Y Mochizuka, Y Suzuki, M Kono, H Hasegawa… - …, 2023 - Wiley Online Library
Abstract Background and Objective Idiopathic pulmonary fibrosis (IPF) is characterized by
progressive lung fibrosis of unknown aetiology. Epidemiological studies have suggested …

Post hoc analysis of clinical outcomes in placebo-and pirfenidone-treated patients with IPF stratified by BMI and weight loss

S Jouneau, B Crestani, R Thibault, M Lederlin… - Respiration, 2022 - karger.com
Background: Weight loss is frequently reported in patients with idiopathic pulmonary fibrosis
(IPF) and may be associated with worse outcomes in these patients. Objective: The aim of …

A systematic review of the prognostic significance of the body mass index in idiopathic pulmonary fibrosis

A Zinellu, C Carru, P Pirina, AG Fois… - Journal of Clinical …, 2023 - mdpi.com
The identification of novel prognostic biomarkers might enhance individualized
management strategies in patients with idiopathic pulmonary fibrosis (IPF). Although several …

Surfactant protein A as a biomarker of outcomes of anti-fibrotic drug therapy in patients with idiopathic pulmonary fibrosis

T Yoshikawa, M Otsuka, H Chiba, K Ikeda, Y Mori… - BMC pulmonary …, 2020 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a progressive and fibrosing lung disease
with poor prognosis. Pirfenidone and nintedanib are anti-fibrotic drugs used for patients with …

[PDF][PDF] Telomerase-positive stem cells as a potential treatment for idiopathic pulmonary fibrosis

HE Young, MO Speight, SE Williams… - Stem Cells Regen …, 2020 - researchgate.net
Idiopathic pulmonary fibrosis (IPF) belongs to a large collection of more than 200 lung
diseases known as interstitial lung diseases (ILD). While the cause of IPF is unknown, it has …

Association between weight loss and mortality in idiopathic pulmonary fibrosis

A Kalininskiy, AR Rackow, D Nagel, D Croft… - Respiratory …, 2022 - Springer
Rationale Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung
disease that has no cure. Many current research efforts center on diagnostic and therapeutic …

Tolerability and efficacy of second-line antifibrotics in patients with idiopathic pulmonary fibrosis

A Cilli, F Uzer, C Sevinç, F Coşkun, A Ursavaş… - Pulmonary …, 2021 - Elsevier
Background The antifibrotic drugs nintedanib and pirfenidone reduce disease progression
in idiopathic pulmonary fibrosis (IPF) and have also shown to improve survival. Switching …