Unraveling the role of miRNAs in the diagnosis, progression, and therapeutic intervention of Alzheimer's disease
Alzheimer's disease (AD) is a multifaceted, advancing neurodegenerative illness that is
responsible for most cases of neurological impairment and dementia in the aged population …
responsible for most cases of neurological impairment and dementia in the aged population …
[HTML][HTML] Levodopa-loaded nanoparticles for the treatment of Parkinson's disease
EF van Vliet, MJ Knol, RM Schiffelers, M Caiazzo… - Journal of Controlled …, 2023 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder characterized by degeneration of
dopaminergic neurons in the substantia nigra pars compacta (SNpc) resulting in dopamine …
dopaminergic neurons in the substantia nigra pars compacta (SNpc) resulting in dopamine …
[HTML][HTML] Transporter-mediated drug delivery
G Gyimesi, MA Hediger - Molecules, 2023 - mdpi.com
Transmembrane transport of small organic and inorganic molecules is one of the
cornerstones of cellular metabolism. Among transmembrane transporters, solute carrier …
cornerstones of cellular metabolism. Among transmembrane transporters, solute carrier …
[HTML][HTML] Potential implications of miRNAs in the pathogenesis, diagnosis, and therapeutics of Alzheimer's disease
L Wang, X Shui, Y Diao, D Chen, Y Zhou… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a complex multifactorial disorder that poses a substantial
burden on patients, caregivers, and society. Considering the increased aging population …
burden on patients, caregivers, and society. Considering the increased aging population …
Neuroprotective effects of lactoferrin in Alzheimer's and Parkinson's diseases: A narrative review
Recent advancements in lactoferrin research have uncovered that lactoferrin does function
not only as an antimicrobial protein but also as an immunomodulatory, anticancer, and …
not only as an antimicrobial protein but also as an immunomodulatory, anticancer, and …
[HTML][HTML] Diagnostic and therapeutic potential of exosomes in neurodegenerative diseases
P Gao, X Li, X Du, S Liu, Y Xu - Frontiers in Aging Neuroscience, 2021 - frontiersin.org
Neurodegenerative diseases are closely related to brain function and the progression of the
diseases are irreversible. Due to brain tissue being not easy to acquire, the study of the …
diseases are irreversible. Due to brain tissue being not easy to acquire, the study of the …
[HTML][HTML] The role of natural flavonoids on neuroinflammation as a therapeutic target for Alzheimer's disease: a narrative review
Q Zhang, Y Yan - Neural Regeneration Research, 2023 - journals.lww.com
Alzheimer's disease is a neurodegenerative disease that affects a large proportion of older
adult people and is characterized by memory loss, progressive cognitive impairment, and …
adult people and is characterized by memory loss, progressive cognitive impairment, and …
Interactions between nanoparticles and pathological changes of vascular in Alzheimer's disease
T Lei, Z Yang, H Li, M Qin, H Gao - Advanced Drug Delivery Reviews, 2024 - Elsevier
Emerging evidence suggests that vascular pathological changes play a pivotal role in the
pathogenesis of Alzheimer's disease (AD). The dysfunction of the cerebral vasculature …
pathogenesis of Alzheimer's disease (AD). The dysfunction of the cerebral vasculature …
[HTML][HTML] Management of brain cancer and neurodegenerative disorders with polymer-based nanoparticles as a biocompatible platform
The blood–brain barrier (BBB) serves as a protective barrier for the central nervous system
(CNS) against drugs that enter the bloodstream. The BBB is a key clinical barrier in the …
(CNS) against drugs that enter the bloodstream. The BBB is a key clinical barrier in the …
[HTML][HTML] Nanotechnology-based gene therapy as a credible tool in the treatment of Alzheimer's disease
Toxic aggregated amyloid-β accumulation is a key pathogenic event in Alzheimer's disease.
Treatment approaches have focused on the suppression, deferral, or dispersion of amyloid …
Treatment approaches have focused on the suppression, deferral, or dispersion of amyloid …