Neurodegenerative disease and brain delivery of therapeutics: Bridging the gap using dendrimers

A Kaur, N Singh, H Kaur, V Kakoty, DS Sharma… - Journal of Drug Delivery …, 2023 - Elsevier
Neurodegenerative diseases (NDs) continue to burden human lives and economic
conditions. They continue to challenge the healthcare system due to the associated …

Cell membrane-based nanomaterials for theranostics of central nervous system diseases

W Li, J Cheng, F He, P Zhang, N Zhang, J Wang… - Journal of …, 2023 - Springer
Central nervous system (CNS) diseases have been widely acknowledged as one of the
major healthy concerns globally, which lead to serious impacts on human health. There will …

[HTML][HTML] Posterity of nanoscience as lipid nanosystems for Alzheimer's disease regression

SS Naser, D Singh, S Preetam, S Kishore, L Kumar… - Materials Today Bio, 2023 - Elsevier
Alzheimer's disease (AD) is a type of dementia that affects a vast number of people around
the world, causing a great deal of misery and death. Evidence reveals a relationship …

[图书][B] CPP, cell-penetrating peptides

Ü Langel - 2019 - Springer
The genesis of cell-penetrating peptide research (CPP; also known as prote/peptide
transduction domains, PTD, or Trojan peptides) was born from the publication of two parallel …

[HTML][HTML] Mechanistic insights into the potential role of dietary polyphenols and their nanoformulation in the management of Alzheimer's disease

HM Albadrani, P Chauhan, S Ashique, MA Babu… - Biomedicine & …, 2024 - Elsevier
Alzheimer's disease (AD) is a very common neurodegenerative disorder associated with
memory loss and a progressive decline in cognitive activity. The two major …

[HTML][HTML] Blood brain barrier-targeted delivery of double selenium nanospheres ameliorates neural ferroptosis in Alzheimer's disease

J Wang, Z Wang, Y Li, Y Hou, C Yin, E Yang, Z Liao… - Biomaterials, 2023 - Elsevier
Alzheimer's disease (AD) as a common neurodegenerative disease showed progressive
cognitive dysfunction and behavioral impairment. Currently, the deposition of amyloid β …

Update on Therapeutic potential of emerging nanoformulations of phytocompounds in Alzheimer's and Parkinson's disease

N Kanojia, K Thapa, G Kaur, A Sharma, V Puri… - Journal of Drug Delivery …, 2023 - Elsevier
The prevalence of neurodegenerative disorders (NDs) has increased recently, with
Parkinson's disease (PD) and Alzheimer's disease (AD) being the two utmost prevalent …

Drug delivery for brains and central nervous system

A Serajian, M Hassanpour, G Heidari - Materials Chemistry Horizons, 2023 - mch.du.ac.ir
This comprehensive review delves into the intricate challenges and recent advancements in
drug delivery to the central nervous system (CNS), with a primary focus on overcoming the …

Targeting reactive astrocytes by pH-responsive ligand-bonded polymeric nanoparticles in spinal cord injury

P Sabourian, M Frounchi, S Kiani… - Drug Delivery and …, 2023 - Springer
In spinal cord injuries, axonal regeneration decreases with the activation of astrocytes
followed by glial scar formation. Targeting reactive astrocytes has been recently performed …

Development and evaluation of multi‐functionalized sialic acid conjugated asiatic acid nanoconstruct to mitigate cognitive deficits in Alzheimer's disease

T Halder, B Saha, N Dhas, S Acharya… - Drug Development …, 2024 - Wiley Online Library
Sialic acid (SA) serves a critical role in neuronal repair and cognitive functions. SA is a nine‐
carbon carboxylated sugar with a glycoconjugate cap that acts as a ligand and surface …