The number of biologics in the therapeutic development pipeline is increasing including
those delivered though inhalation (Morales, 2017; Fathe, 2016). Biologics comprise a broad …

Inhalation therapy can effectively treat chronic obstructive pulmonary disease (COPD), but
the physical factors determining the appropriate aerosol delivery into the targeted airways …

Purpose To develop an in vitro method to rapidly evaluate regional lung doses delivered by
pharmaceutical inhalers. Currently, cascade impactor measurements are used, but these …

Dry powder inhalers are used by a large number of patients worldwide to treat respiratory
diseases. The objective of this work is to experimentally investigate changes in aerosol …

Dry powder inhalers (DPIs) are the first choice for inhalation drug development. However,
some conventional DPI formulation processes require heating, which may damage high …

Although inhalation therapy represents a promising drug delivery route for the treatment of
respiratory diseases, the real-time evaluation of lung drug deposition remains an area yet to …

Background: Budesonide (BUD)/formoterol (FM) dry powder inhaler has a feature that the
fine particle fraction output is dependent on users' inspiratory flow rate. The aim of this study …

It is well known that correct use of inhalers plays a critical role in optimal inhalation therapy,
but the impact of incorrect inhaler use on pulmonary drug delivery has not been …

To the Editor: We have read with great interest the article by Alahmadi et al, 1 which
demonstrated the relationship of serum inhaled corticosteroid (ICS) levels and exacerbation …

To achieve adequate inhalation therapy, a proper inhalation technique is needed in clinical
practice. However, there is limited information on proper inhalation flow patterns of …