Conservative versus early surgical treatment in the management of pyogenic spondylodiscitis: a systematic review and meta-analysis

SG Thavarajasingam, KV Vemulapalli, S Vishnu K… - Scientific reports, 2023 - nature.com
Spondylodiscitis is the commonest spine infection, and pyogenic spondylodiscitis is the most
common subtype. Whilst antibiotic therapy is the mainstay of treatment, some advocate that …

a safety profile of dalbavancin for on-and off-label utilization

O Simonetti, G Rizzetto, E Molinelli… - … and Clinical Risk …, 2021 - Taylor & Francis
Introduction Dalbavancin is a bactericidal lipoglycopeptide active against gram-positives. Its
use has been approved for the treatment of acute bacterial skin and skin structure infections …

The epidemiology of spondylodiscitis in Germany: a descriptive report of incidence rates, pathogens, in-hospital mortality, and hospital stays between 2010 and 2020

S Lang, N Walter, M Schindler, S Baertl… - Journal of Clinical …, 2023 - mdpi.com
Background: Spondylodiscitis can lead to significant morbidity and mortality. Understanding
its up-to-date epidemiological characteristics and trends is important to improve patient care …

Clinical application value of metagenomic next-generation sequencing in the diagnosis of spinal infections and its impact on clinical outcomes

G Zhang, H Zhang, XJ Hu, D Xu, B Tang… - Frontiers in Cellular …, 2023 - frontiersin.org
This study aimed to evaluate the impact of precise treatment administered according to the
results of metagenomic next-generation sequencing (mNGS) on the clinical outcomes of …

Axial spondyloarthritis: mimics and pitfalls of imaging assessment

AP Caetano, VV Mascarenhas, PM Machado - Frontiers in Medicine, 2021 - frontiersin.org
Axial spondyloarthritis (axSpA) is a chronic inflammatory disorder that predominantly
involves the axial skeleton. Imaging findings of axSpA can be divided into active changes …

Diagnosis of vertebral osteomyelitis

J Maamari, AJ Tande, F Diehn, DBG Tai… - Journal of bone and …, 2022 - jbji.copernicus.org
Native vertebral osteomyelitis (NVO) is a potentially fatal infection which has seen a gradual
increase in its incidence over the past decades. The infection is insidious, presenting with …

MRI in differential diagnosis between tuberculous and pyogenic spondylodiscitis

N Naselli, G Facchini, GM Lima, G Evangelisti… - European Spine …, 2022 - Springer
Purpose The aim of the study was to investigate whether MRI findings together with
epidemiological data could help in differentiating between tuberculous and pyogenic …

Oedema on STIR modified the effect of amoxicillin as treatment for chronic low back pain with Modic changes—subgroup analysis of a randomized trial

PM Kristoffersen, LCH Bråten, N Vetti, L Grøvle… - European …, 2021 - Springer
Objective To evaluate potential MRI-defined effect modifiers of amoxicillin treatment in
patients with chronic low back pain and type 1 or 2 Modic changes (MCs) at the level of a …

[HTML][HTML] Spondylodiscitis presenting to a chiropractor: a case report and literature review

ECP Chu, RJ Trager, SJM Goh, JSF Shum - Cureus, 2023 - ncbi.nlm.nih.gov
An 80-year-old man under combination therapy for pulmonary tuberculosis presented to a
chiropractor with a one-month history of worsening chronic low back pain, yet denied having …

Brucella Spondylitis: Current Knowledge and Recent Advances

N Spernovasilis, A Karantanas, I Markaki… - Journal of Clinical …, 2024 - mdpi.com
The most prevalent zoonotic disease is brucellosis, which poses a significant threat for
worldwide public health. Particularly in endemic areas, spinal involvement is a major source …