[HTML][HTML] Pleural mesothelioma classification—update and challenges
S Dacic - Modern Pathology, 2022 - Elsevier
Mesothelial tumors are classified into benign or preinvasive tumors, and mesotheliomas.
The benign or preinvasive group includes adenomatoid tumors, well-differentiated papillary …
The benign or preinvasive group includes adenomatoid tumors, well-differentiated papillary …
Pleural mesothelioma classification update
MB Beasley, F Galateau-Salle, S Dacic - Virchows Archiv, 2021 - Springer
The 2015 WHO classification of pleural mesotheliomas includes three major histologic
subtypes—epithelioid, sarcomatoid, and biphasic. Recent genomic data has supported the …
subtypes—epithelioid, sarcomatoid, and biphasic. Recent genomic data has supported the …
Treatment of malignant pleural mesothelioma: American Society of Clinical Oncology clinical practice guideline
HL Kindler, N Ismaila, SG Armato III… - Journal of Clinical …, 2018 - ascopubs.org
Purpose To provide evidence-based recommendations to practicing physicians and others
on the management of malignant pleural mesothelioma. Methods ASCO convened an …
on the management of malignant pleural mesothelioma. Methods ASCO convened an …
[HTML][HTML] Update on biology and management of mesothelioma
R Asciak, V George, NM Rahman - European Respiratory …, 2021 - Eur Respiratory Soc
Malignant pleural mesothelioma is an aggressive, incurable cancer that is usually caused by
asbestos exposure several decades before symptoms arise. Despite widespread prohibition …
asbestos exposure several decades before symptoms arise. Despite widespread prohibition …
[HTML][HTML] Pembrolizumab as palliative immunotherapy in malignant pleural mesothelioma
Y Metaxas, G Rivalland, LA Mauti, D Klingbiel… - Journal of Thoracic …, 2018 - Elsevier
Introduction There is no approved second-line treatment for malignant pleural mesothelioma
(MPM). On the basis of promising early results, pembrolizumab was used off-label in …
(MPM). On the basis of promising early results, pembrolizumab was used off-label in …
NCCN guidelines insights: malignant pleural mesothelioma, version 3.2016
These NCCN Guidelines Insights focus on recent updates to the NCCN Guidelines for
Malignant Pleural Mesothelioma (MPM). These NCCN Guidelines Insights discuss systemic …
Malignant Pleural Mesothelioma (MPM). These NCCN Guidelines Insights discuss systemic …
[HTML][HTML] Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of lung cancer and mesothelioma
R Govindan, C Aggarwal, SJ Antonia… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Immunotherapy has transformed lung cancer care in recent years. In addition to providing
durable responses and prolonged survival outcomes for a subset of patients with heavily …
durable responses and prolonged survival outcomes for a subset of patients with heavily …
Pegargiminase Plus First-Line Chemotherapy in Patients With Nonepithelioid Pleural Mesothelioma: The ATOMIC-Meso Randomized Clinical Trial
PW Szlosarek, BC Creelan, T Sarkodie, L Nolan… - JAMA …, 2024 - jamanetwork.com
Importance Arginine deprivation using ADI-PEG20 (pegargiminase) combined with
chemotherapy is untested in a randomized study among patients with cancer. ATOMIC …
chemotherapy is untested in a randomized study among patients with cancer. ATOMIC …
[HTML][HTML] The highly selective and oral phosphoinositide 3-kinase delta (PI3K-δ) inhibitor roginolisib induces apoptosis in mesothelioma cells and increases immune …
C Kalla, G Ott, F Finotello, K Niewola-Staszkowska… - Translational …, 2024 - Elsevier
Targeting aberrantly expressed kinases in malignant pleural mesothelioma (MPM) is a
promising therapeutic strategy. We here investigated the effect of the novel and highly …
promising therapeutic strategy. We here investigated the effect of the novel and highly …
Use of preclinical models for malignant pleural mesothelioma
Malignant pleural mesothelioma (MPM) is an aggressive cancer most commonly caused by
prior exposure to asbestos. Median survival is 12–18 months, since surgery is ineffective …
prior exposure to asbestos. Median survival is 12–18 months, since surgery is ineffective …