Integrated MRI-guided radiotherapy—opportunities and challenges

PJ Keall, C Brighi, C Glide-Hurst, G Liney… - Nature Reviews …, 2022 - nature.com
MRI can help to categorize tissues as malignant or non-malignant both anatomically and
functionally, with a high level of spatial and temporal resolution. This non-invasive imaging …

Adaptive radiotherapy for anatomical changes

JJ Sonke, M Aznar, C Rasch - Seminars in radiation oncology, 2019 - Elsevier
The anatomy of cancer patients changes between radiation treatment planning and delivery
as well as over the course of radiotherapy. Adaptive radiotherapy (ART) aims to deliver …

MRI-guided radiation therapy: an emerging paradigm in adaptive radiation oncology

R Otazo, P Lambin, JP Pignol, ME Ladd… - Radiology, 2021 - pubs.rsna.org
Radiation therapy (RT) continues to be one of the mainstays of cancer treatment.
Considerable efforts have been recently devoted to integrating MRI into clinical RT planning …

Quantitative radiomics studies for tissue characterization: a review of technology and methodological procedures

RTHM Larue, G Defraene… - The British journal of …, 2017 - academic.oup.com
Quantitative analysis of tumour characteristics based on medical imaging is an emerging
field of research. In recent years, quantitative imaging features derived from CT, positron …

The transformation of radiation oncology using real-time magnetic resonance guidance: A review

WA Hall, ES Paulson, UA van der Heide… - European Journal of …, 2019 - Elsevier
Radiation therapy (RT) is an essential component of effective cancer care and is used
across nearly all cancer types. The delivery of RT is becoming more precise through rapid …

Medical physics challenges in clinical MR-guided radiotherapy

C Kurz, G Buizza, G Landry, F Kamp, M Rabe… - Radiation …, 2020 - Springer
The integration of magnetic resonance imaging (MRI) for guidance in external beam
radiotherapy has faced significant research and development efforts in recent years. The …

Emerging role of MRI in radiation therapy

H Chandarana, H Wang, RHN Tijssen… - Journal of Magnetic …, 2018 - Wiley Online Library
Advances in multimodality imaging, providing accurate information of the irradiated target
volume and the adjacent critical structures or organs at risk (OAR), has made significant …

[HTML][HTML] Two-and-a-half-year clinical experience with the world's first magnetic resonance image guided radiation therapy system

BW Fischer-Valuck, L Henke, O Green… - Advances in radiation …, 2017 - Elsevier
Purpose Magnetic resonance image guided radiation therapy (MR-IGRT) has been used at
our institution since 2014. We report on more than 2 years of clinical experience in treating …

Chloroquine combined with concurrent radiotherapy and temozolomide for newly diagnosed glioblastoma: a phase IB trial

I Compter, DBP Eekers, A Hoeben, KMA Rouschop… - Autophagy, 2021 - Taylor & Francis
Treatment of glioblastoma xenografts with chloroquine results in macroautophagy/
autophagy inhibition, resulting in a reduction of tumor hypoxia and sensitization to radiation …

Stability of radiomics features in apparent diffusion coefficient maps from a multi-centre test-retest trial

J Peerlings, HC Woodruff, JM Winfield, A Ibrahim… - Scientific reports, 2019 - nature.com
Quantitative radiomics features, extracted from medical images, characterize tumour-
phenotypes and have been shown to provide prognostic value in predicting clinical …