Engineering cells for precision drug delivery: New advances, clinical translation, and emerging strategies
Cells have emerged as a promising new form of drug delivery carriers owing to their
distinguished advantages such as naturally bypassing immune recognition, intrinsic …
distinguished advantages such as naturally bypassing immune recognition, intrinsic …
In situ cellular hitchhiking of nanoparticles for drug delivery
Since the inception of the concept of “magic bullet”, nanoparticles have evolved to be one of
the most effective carriers in drug delivery. Nanoparticles improve the therapeutic efficacy of …
the most effective carriers in drug delivery. Nanoparticles improve the therapeutic efficacy of …
Nanoparticles hitchhike on monocytes for glioblastoma treatment after low-dose radiotherapy
J Kuang, ZY Rao, DW Zheng, D Kuang, QX Huang… - ACS …, 2023 - ACS Publications
Glioblastomas (GBMs) are aggressive primary brain tumors with fatal outcome. Traditional
chemo-radiotherapy has poor therapeutic effect and significant side effects, due to the drug …
chemo-radiotherapy has poor therapeutic effect and significant side effects, due to the drug …
Current understanding of passive and active targeting nanomedicines to enhance tumor accumulation
Z Chen, RK Kankala, L Long, S Xie, AZ Chen… - Coordination Chemistry …, 2023 - Elsevier
In recent years, tremendous advancements in nanomedicine have resulted in the rapid
development of various nanoformulations, especially the treatment of solid tumors. Despite …
development of various nanoformulations, especially the treatment of solid tumors. Despite …
Systemic tumor suppression via macrophage‐driven automated homing of metal‐phenolic‐gated nanosponges for metastatic melanoma
X Liao, G Gong, M Dai, Z Xiang, J Pan, X He… - Advanced …, 2023 - Wiley Online Library
Cell‐based therapies comprising the administration of living cells to patients for direct
therapeutic activities have experienced remarkable success in the clinic, of which …
therapeutic activities have experienced remarkable success in the clinic, of which …
Knowledge gaps in generating cell-based drug delivery systems and a possible meeting with artificial intelligence
N Mozafari, N Mozafari, A Dehshahri… - Molecular …, 2023 - ACS Publications
Cell-based drug delivery systems are new strategies in targeted delivery in which cells or
cell-membrane-derived systems are used as carriers and release their cargo in a controlled …
cell-membrane-derived systems are used as carriers and release their cargo in a controlled …
Exosomes-based nanomedicine for neurodegenerative diseases: current insights and future challenges
A Cano, Á Muñoz-Morales, E Sánchez-López… - Pharmaceutics, 2023 - mdpi.com
Neurodegenerative diseases constitute a group of pathologies whose etiology remains
unknown in many cases, and there are no treatments that stop the progression of such …
unknown in many cases, and there are no treatments that stop the progression of such …
“Hook&Loop” multivalent interactions based on disk-shaped nanoparticles strengthen active targeting
How to enhance active targeting efficiency remains a challenge. Multivalent interactions play
a crucial role in improving the binding ability between ligands and receptors. It is …
a crucial role in improving the binding ability between ligands and receptors. It is …
Biomimetic nano-drug delivery system: an emerging platform for promoting tumor treatment
X Han, C Gong, Q Yang, K Zheng, Z Wang… - International Journal of …, 2024 - Taylor & Francis
With the development of nanotechnology, nanoparticles (NPs) have shown broad prospects
as drug delivery vehicles. However, they exhibit certain limitations, including low …
as drug delivery vehicles. However, they exhibit certain limitations, including low …
[HTML][HTML] Diverse drug delivery systems for the enhancement of cancer immunotherapy: an overview
X Liu, Y Cheng, Y Liu, X Hu, T Wen - Frontiers in Immunology, 2024 - frontiersin.org
Despite the clear benefits demonstrated by immunotherapy, there is still an inevitable off-
target effect resulting in serious adverse immune reactions. In recent years, the research and …
target effect resulting in serious adverse immune reactions. In recent years, the research and …