The 5-HT2A serotonin receptor in executive function: Implications for neuropsychiatric and neurodegenerative diseases
S Aznar, MES Hervig - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
Executive function entails the interplay of a group of cognitive processes enabling the
individual to anticipate consequences, attain self-control, and undertake appropriate goal …
individual to anticipate consequences, attain self-control, and undertake appropriate goal …
Different decision deficits impair response inhibition in progressive supranuclear palsy and Parkinson's disease
Progressive supranuclear palsy and Parkinson's disease have distinct underlying
neuropathology, but both diseases affect cognitive function in addition to causing a …
neuropathology, but both diseases affect cognitive function in addition to causing a …
[HTML][HTML] Prefrontal cortical connectivity mediates locus coeruleus noradrenergic regulation of inhibitory control in older adults
Response inhibition is a core executive function enabling adaptive behavior in dynamic
environments. Human and animal models indicate that inhibitory control and control …
environments. Human and animal models indicate that inhibitory control and control …
Linking neuroscience with modern concepts of impulse control disorders in Parkinson's disease
Patients with Parkinson's disease (PD) may experience impulse control disorders (ICDs)
when on dopamine agonist therapy for their motor symptoms. In the last few years, a rapid …
when on dopamine agonist therapy for their motor symptoms. In the last few years, a rapid …
Reorganization of cortical oscillatory dynamics underlying disinhibition in frontotemporal dementia
The distribution of pathology in frontotemporal dementia is anatomically selective, to distinct
cortical regions and with differential neurodegeneration across the cortical layers. The …
cortical regions and with differential neurodegeneration across the cortical layers. The …
[HTML][HTML] The neuroanatomical and neurochemical basis of apathy and impulsivity in frontotemporal lobar degeneration
L Passamonti, CJ Lansdall, JB Rowe - Current opinion in behavioral …, 2018 - Elsevier
Highlights•Apathy and impulsivity are common consequences of frontotemporal lobar
degeneration syndromes.•Common frontostriatal loops mediate different modes of apathy …
degeneration syndromes.•Common frontostriatal loops mediate different modes of apathy …
Improving response inhibition systems in frontotemporal dementia with citalopram
LE Hughes, T Rittman, R Regenthal, TW Robbins… - Brain, 2015 - academic.oup.com
Disinhibition is a cardinal feature of the behavioural variant of frontotemporal dementia,
presenting as impulsive and impetuous behaviours that are often difficult to manage. The …
presenting as impulsive and impetuous behaviours that are often difficult to manage. The …
Impaired corticostriatal connectivity in impulse control disorders in Parkinson disease
N Carriere, R Lopes, L Defebvre, C Delmaire… - Neurology, 2015 - AAN Enterprises
Objectives: To compare the striatum's resting-state functional connectivity in patients with
Parkinson disease (PD) with and without impulse control disorders (ICDs). Methods: Twenty …
Parkinson disease (PD) with and without impulse control disorders (ICDs). Methods: Twenty …
[HTML][HTML] Trajectories and contributing factors of neural compensation in healthy and pathological aging
Neural degeneration is a hallmark of healthy aging and can be associated with specific
cognitive impairments. However, neural degeneration per se is not matched by unremitting …
cognitive impairments. However, neural degeneration per se is not matched by unremitting …
Cognition in Parkinson's disease
C O'Callaghan, SJG Lewis - International review of neurobiology, 2017 - Elsevier
Cognitive decline is now recognized as a common nonmotor symptom of Parkinson's
disease, and it has been the subject of increasing research in recent decades. Cognitive …
disease, and it has been the subject of increasing research in recent decades. Cognitive …