The 5-HT2A serotonin receptor in executive function: Implications for neuropsychiatric and neurodegenerative diseases

S Aznar, MES Hervig - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
Executive function entails the interplay of a group of cognitive processes enabling the
individual to anticipate consequences, attain self-control, and undertake appropriate goal …

Different decision deficits impair response inhibition in progressive supranuclear palsy and Parkinson's disease

J Zhang, T Rittman, C Nombela, A Fois… - Brain, 2016 - academic.oup.com
Progressive supranuclear palsy and Parkinson's disease have distinct underlying
neuropathology, but both diseases affect cognitive function in addition to causing a …

[HTML][HTML] Prefrontal cortical connectivity mediates locus coeruleus noradrenergic regulation of inhibitory control in older adults

A Tomassini, FH Hezemans, R Ye… - Journal of …, 2022 - Soc Neuroscience
Response inhibition is a core executive function enabling adaptive behavior in dynamic
environments. Human and animal models indicate that inhibitory control and control …

Linking neuroscience with modern concepts of impulse control disorders in Parkinson's disease

TC Napier, JC Corvol, AA Grace… - Movement …, 2015 - Wiley Online Library
Patients with Parkinson's disease (PD) may experience impulse control disorders (ICDs)
when on dopamine agonist therapy for their motor symptoms. In the last few years, a rapid …

Reorganization of cortical oscillatory dynamics underlying disinhibition in frontotemporal dementia

LE Hughes, T Rittman, TW Robbins, JB Rowe - Brain, 2018 - academic.oup.com
The distribution of pathology in frontotemporal dementia is anatomically selective, to distinct
cortical regions and with differential neurodegeneration across the cortical layers. The …

[HTML][HTML] The neuroanatomical and neurochemical basis of apathy and impulsivity in frontotemporal lobar degeneration

L Passamonti, CJ Lansdall, JB Rowe - Current opinion in behavioral …, 2018 - Elsevier
Highlights•Apathy and impulsivity are common consequences of frontotemporal lobar
degeneration syndromes.•Common frontostriatal loops mediate different modes of apathy …

Improving response inhibition systems in frontotemporal dementia with citalopram

LE Hughes, T Rittman, R Regenthal, TW Robbins… - Brain, 2015 - academic.oup.com
Disinhibition is a cardinal feature of the behavioural variant of frontotemporal dementia,
presenting as impulsive and impetuous behaviours that are often difficult to manage. The …

Impaired corticostriatal connectivity in impulse control disorders in Parkinson disease

N Carriere, R Lopes, L Defebvre, C Delmaire… - Neurology, 2015 - AAN Enterprises
Objectives: To compare the striatum's resting-state functional connectivity in patients with
Parkinson disease (PD) with and without impulse control disorders (ICDs). Methods: Twenty …

[HTML][HTML] Trajectories and contributing factors of neural compensation in healthy and pathological aging

N Bunzeck, TK Steiger, UM Krämer, K Luedtke… - Neuroscience & …, 2023 - Elsevier
Neural degeneration is a hallmark of healthy aging and can be associated with specific
cognitive impairments. However, neural degeneration per se is not matched by unremitting …

Cognition in Parkinson's disease

C O'Callaghan, SJG Lewis - International review of neurobiology, 2017 - Elsevier
Cognitive decline is now recognized as a common nonmotor symptom of Parkinson's
disease, and it has been the subject of increasing research in recent decades. Cognitive …