[HTML][HTML] Radiation-induced lung injury (RILI)

L Giuranno, J Ient, D De Ruysscher, MA Vooijs - Frontiers in oncology, 2019 - frontiersin.org
Radiation pneumonitis (RP) and radiation fibrosis (RF) are two dose-limiting toxicities of
radiotherapy (RT), especially for lung, and esophageal cancer. It occurs in 5–20% of …

Radiation-related thyroid cancer

V Saenko, N Mitsutake - Endocrine reviews, 2024 - academic.oup.com
Radiation is an environmental factor that elevates the risk of developing thyroid cancer.
Actual and possible scenarios of exposures to external and internal radiation are multiple …

[HTML][HTML] Current knowledge of germline genetic risk factors for the development of non-medullary thyroid cancer

K Hińcza, A Kowalik, A Kowalska - Genes, 2019 - mdpi.com
The thyroid is the most common site of endocrine cancer. One type of thyroid cancer, non-
medullary thyroid cancer (NMTC), develops from follicular cells and represents …

The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl

M Takahashi, VA Saenko… - Human molecular …, 2010 - academic.oup.com
Papillary thyroid cancer (PTC) among individuals exposed to radioactive iodine in their
childhood or adolescence is a major internationally recognized health consequence of the …

Low-dose radiation exposure and carcinogenesis

K Suzuki, S Yamashita - Japanese journal of clinical oncology, 2012 - academic.oup.com
Absorption of energy from ionizing radiation by the genetic material in the cell leads to
damage to DNA, which in turn leads to cell death, chromosome aberrations and gene …

[HTML][HTML] Pharmacogenetics of toxicity of 5-fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer patients

K Tecza, J Pamula-Pilat, J Lanuszewska… - Oncotarget, 2018 - ncbi.nlm.nih.gov
The differences in patients' response to the same medication, toxicity included, are one of
the major problems in breast cancer treatment. Chemotherapy toxicity makes a significant …

[HTML][HTML] Ghrelin and lipid metabolism: key partners in energy balance

L Varela, MJ Vázquez, F Cordido… - Journal of …, 2011 - jme.bioscientifica.com
It is widely accepted that thyroid cancer is strongly determined by the individual genetic
background. In this regard, it is expected that sporadic thyroid cancer is the result of multiple …

Genetic variation as a modifier of association between therapeutic exposure and subsequent malignant neoplasms in cancer survivors

S Bhatia - Cancer, 2015 - Wiley Online Library
Subsequent malignant neoplasms (SMNs) are associated with significant morbidity and are
a major cause of premature mortality among cancer survivors. Several large studies have …

Clinical and pathological implications of concurrent autoimmune thyroid disorders and papillary thyroid cancer

LL Cunha, RC Ferreira, MA Marcello… - Journal of thyroid …, 2011 - Wiley Online Library
Cooccurrences of chronic lymphocytic thyroiditis (CLT) and thyroid cancer (DTC) have been
repeatedly reported. Both CLT and DTC, mainly papillary thyroid carcinoma (PTC), share …

[HTML][HTML] Clinical and functional assays of radiosensitivity and radiation-induced second cancer

M Habash, LC Bohorquez, E Kyriakou, T Kron… - Cancers, 2017 - mdpi.com
Whilst the near instantaneous physical interaction of radiation energy with living cells leaves
little opportunity for inter-individual variation in the initial yield of DNA damage, all the …