Alzheimer's disease is characterized by the aggregation of β-amyloid, a pathological feature
believed to drive the neuronal loss and cognitive decline commonly seen in the disease …

Background Use proton magnetic resonance spectroscopy (1H-MRS) non invasive
technique to assess the modifications of glutamate-glutamine (Glx) and gammaaminobutyric …

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central
nervous system. In the mature brain, inhibitory GABAergic signaling is critical in maintaining …

The goal of the treatment for Alzheimer's dementia (AD) is the cure of dementia. A literature
review revealed 18 major elements causing AD and 29 separate medications that address …

Bipolar disorder is a chronic disorder characterized by fluctuations in mood state and energy
and recurrent episodes of mania/hypomania and depression. Bipolar disorder may be …

Introduction: Alzheimer's disease (AD) is a common neurodegenerative disorder and the
primary cause of dementia. Considerable evidence supports the “amyloid hypothesis,” …

Hippocamposeptal (HS) neurons send GABAergic projections from the hippocampus to the
medial septum/diagonal band of Broca (MS/DBB) as part of a reciprocal loop that is critical …

Several proteases are involved in the proteolytic processing of the amyloid precursor protein
(APP) generating the amyloidogenic Aβ peptide, which can act as the triggering pathological …

Dysbiosis of the microbiome correlates with many neurological disorders, yet very little is
known about the chemistry that controls the production of neuromodulatory molecules by gut …

Dynamic and rapid reconfigurations of neural activation patterns, known as brain states,
support cognition. Recent analytic advances applied to functional magnetic resonance …