Bronchial epithelium as a target for innovative treatments in asthma

D Gras, P Chanez, I Vachier, A Petit… - Pharmacology & …, 2013 - Elsevier
Increasing evidence of a critical role played by the bronchial epithelium in airway
homeostasis is opening new therapeutic avenues. Its unique situation at the interface with …

[HTML][HTML] Cytokine production and signaling pathways in respiratory virus infection

H Kimura, M Yoshizumi, H Ishii, K Oishi… - Frontiers in …, 2013 - frontiersin.org
It has been confirmed that respiratory virus infections can induce abberant cytokine
production in the host. These cytokines may be associated with both elimination of the virus …

[HTML][HTML] Biological clustering supports both “Dutch” and “British” hypotheses of asthma and chronic obstructive pulmonary disease

MA Ghebre, M Bafadhel, D Desai, SE Cohen… - Journal of Allergy and …, 2015 - Elsevier
Background Asthma and chronic obstructive pulmonary disease (COPD) are heterogeneous
diseases. Objective We sought to determine, in terms of their sputum cellular and mediator …

Clinical and inflammatory phenotyping by breathomics in chronic airway diseases irrespective of the diagnostic label

R De Vries, YWF Dagelet, P Spoor… - European …, 2018 - Eur Respiratory Soc
Asthma and chronic obstructive pulmonary disease (COPD) are complex and overlapping
diseases that include inflammatory phenotypes. Novel anti-eosinophilic/anti-neutrophilic …

[HTML][HTML] Dual transcriptomic profiling of host and microbiota during health and disease in pediatric asthma

M Pérez-Losada, E Castro-Nallar, ML Bendall… - PloS one, 2015 - journals.plos.org
Background High-throughput sequencing (HTS) analysis of microbial communities from the
respiratory airways has heavily relied on the 16S rRNA gene. Given the intrinsic limitations …

[HTML][HTML] Tear cytokine profile as a noninvasive biomarker of inflammation for ocular surface diseases: standard operating procedures

Y Wei, N Gadaria-Rathod, S Epstein… - … & visual science, 2013 - iovs.arvojournals.org
Purpose.: To provide standard operating procedures (SOPs) for measuring tear
inflammatory cytokine concentrations and to validate the resulting profile as a minimally …

Peptides in pepsin–pancreatin hydrolysates from commercially available soy products that inhibit lipopolysaccharide-induced inflammation in macrophages

VP Dia, NA Bringe, EG De Mejia - Food chemistry, 2014 - Elsevier
The potential of pepsin–pancreatin hydrolysates, from different foods, to inhibit inflammation
using lipopolysaccharide (LPS)-induced RAW 264.7 macrophages as an in vitro model was …

Thymol attenuates allergic airway inflammation in ovalbumin (OVA)-induced mouse asthma

E Zhou, Y Fu, Z Wei, Y Yu, X Zhang, Z Yang - Fitoterapia, 2014 - Elsevier
Thymol, a naturally occurring monocyclic phenolic compound derived from Thymus vulgaris
(Lamiaceae), has been reported to exhibit anti-inflammatory property in vivo and vitro …

Risk factors for premenstrual asthma: a systematic review and meta-analysis

JL Sánchez-Ramos, AR Pereira-Vega… - Expert Review of …, 2017 - Taylor & Francis
Introduction: Asthma in women can deteriorate in specific phases during the menstrual
cycle. Deterioration in the premenstrual phase (increase in symptoms or deterioration in …

IL-1β: a key modulator in asthmatic airway smooth muscle hyper-reactivity

Z Liao, H Xiao, Y Zhang, RS Tong… - Expert review of …, 2015 - Taylor & Francis
Asthma is a chronic inflammatory disorder of the airway. It is characterized by airway hyper-
reactivity, which can be attributed to the chronically inflamed airway. However, the molecular …