[HTML][HTML] Lithium treatment over the lifespan in bipolar disorders

C Volkmann, T Bschor, S Köhler - Frontiers in Psychiatry, 2020 - frontiersin.org
Lithium has been the treatment of choice for patients with bipolar disorder (BD) for nearly 70
years. It is recommended by all relevant guidelines as a first-line treatment for maintenance …

[HTML][HTML] Toward precision medicine in ADHD

J Buitelaar, S Bölte, D Brandeis, A Caye… - Frontiers in behavioral …, 2022 - frontiersin.org
Attention-Deficit Hyperactivity Disorder (ADHD) is a complex and heterogeneous
neurodevelopmental condition for which curative treatments are lacking. Whilst …

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients …

LN Yatham, SH Kennedy, SV Parikh… - Bipolar …, 2018 - Wiley Online Library
The Canadian Network for Mood and Anxiety Treatments (CANMAT) previously published
treatment guidelines for bipolar disorder in 2005, along with international commentaries and …

The clinical characterization of the adult patient with bipolar disorder aimed at personalization of management

RS McIntyre, M Alda, RJ Baldessarini, M Bauer… - World …, 2022 - Wiley Online Library
Bipolar disorder is heterogeneous in phenomenology, illness trajectory, and response to
treatment. Despite evidence for the efficacy of multimodality interventions, the majority of …

Trends in the incidence and DALYs of bipolar disorder at global, regional, and national levels: results from the global burden of Disease Study 2017

H He, C Hu, Z Ren, L Bai, F Gao, J Lyu - Journal of psychiatric research, 2020 - Elsevier
The objective of this study is to assess the global, regional, and national burden of bipolar
disorder (BPD) from 1990 to 2017, by gender, age, and social-demographic index (SDI) from …

Resting-state functional connectivity and spontaneous brain activity in early-onset bipolar disorder: a review of functional magnetic resonance imaging studies

G Cattarinussi, M Bellani, E Maggioni… - Journal of Affective …, 2022 - Elsevier
Background Early-onset bipolar disorder (BD) is a complex psychiatric illness characterized
by mood swings, irritability and functional impairments. To improve our understanding of the …

[HTML][HTML] Association of polygenic risk for bipolar disorder with grey matter structure and white matter integrity in youth

X Jiang, CC Zai, KG Kennedy, Y Zou… - Translational …, 2023 - nature.com
There is a gap in knowledge regarding the polygenic underpinnings of brain anomalies
observed in youth bipolar disorder (BD). This study examined the association of a polygenic …

Neural signatures of the risk for bipolar disorder: a meta‐analysis of structural and functional neuroimaging studies

G Cattarinussi, A Di Giorgio, RC Wolf… - Bipolar …, 2019 - Wiley Online Library
Objective Widespread functional and structural alterations in the brain have been
extensively reported in unaffected relatives (RELs) of patients with bipolar disorder (BD) who …

Excitability and irritability in preschoolers predicts later psychopathology: The importance of positive and negative emotion dysregulation

AC Vogel, JJ Jackson, DM Barch, R Tillman… - Development and …, 2019 - cambridge.org
Emotion dysregulation is a risk factor for the development of a variety of psychopathologic
outcomes. In children, irritability, or dysregulated negative affect, has been the primary focus …

Role of polygenic risk score in the familial transmission of bipolar disorder in youth

B Birmaher, D Hafeman, J Merranko, A Zwicker… - JAMA …, 2022 - jamanetwork.com
Importance Establishing genetic contributions to the transmission of bipolar disorder (BD)
from parents to offspring may inform the risk of developing this disorder and further serve to …