Glycosaminoglycans: what remains to be deciphered?

S Perez, O Makshakova, J Angulo, E Bedini, A Bisio… - Jacs Au, 2023 - ACS Publications
Glycosaminoglycans (GAGs) are complex polysaccharides exhibiting a vast structural
diversity and fulfilling various functions mediated by thousands of interactions in the …

Hyaluronic acid-based prodrug nanomedicines for enhanced tumor targeting and therapy: A review

R Zhang, X Zhao, A Jia, C Wang, H Jiang - International Journal of …, 2023 - Elsevier
Hyaluronic acid (HA) represents a natural polysaccharide which has attracted significant
attention owing to its improved tumor targeting capacity, enzyme degradation capacity, and …

Advanced polymer hydrogels that promote diabetic ulcer healing: mechanisms, classifications, and medical applications

Y Xu, Q Hu, Z Wei, Y Ou, Y Cao, H Zhou… - Biomaterials …, 2023 - spj.science.org
Diabetic ulcers (DUs) are one of the most serious complications of diabetes mellitus. The
application of a functional dressing is a crucial step in DU treatment and is associated with …

Technology and functional insights into the nicotinamide mononucleotide for human health

Y Liu, JS Gong, G Marshall, C Su, JS Shi… - Applied Microbiology and …, 2023 - Springer
Nicotinamide mononucleotide (NMN), a naturally occurring biologically active nucleotide,
mainly functions via mediating the biosynthesis of NAD+. In recent years, its excellent …

Novel β1,4 N-acetylglucosaminyltransferase in de novo enzymatic synthesis of hyaluronic acid oligosaccharides

JY Sun, JQ Deng, RR Du, SY Xin, YL Cao, Z Lu… - Applied Microbiology …, 2023 - Springer
The efficiency of de novo synthesis of hyaluronic acid (HA) using Pasteurella multocida
hyaluronate synthase (PmHAS) is limited by its low catalytic activity during the initial reaction …

Evaluation of Saxifraga stolonifera phenolic extracts as a potential antivenom against Deinagkistrodon acutus venom: in vitro and in vivo studies

ZT Liu, Y Zhang, R Fang, M Simmonds… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance In the snake-infested mountainous regions of China,
Saxifraga stolonifera [L.] Meeb is widely utilized as an immediate remedy for venomous …

High-Level Extracellular Expression of Hyaluronate Lyase HylP in Bacillus subtilis for Hyaluronan Degradation

L Zhu, S Li, JY Jiang, ZY Yao, Q Li, SJ Lian… - Applied Biochemistry …, 2024 - Springer
Hyaluronate lyase (HA lyase) has potential in the industrial processing of hyaluronan. In this
study, HylP, an HA lyase from Streptococcus pyogenes phage (SPB) was successfully …

Saccharide mapping as an extraordinary method on characterization and identification of plant and fungi polysaccharides: A review

Y Ma, L Zhang, X Ma, K Bai, Z Tian, Z Wang… - International Journal of …, 2024 - Elsevier
Saccharide mapping was a promising scheme to unveil the mystery of polysaccharide
structure by analysis of the fragments generated from polysaccharide decomposition …

Polyphenol-mediated hyaluronic acid/tannic acid hydrogel with short gelation time and high adhesion strength for accelerating wound healing

X Jin, C Wei, K Li, P Yin, C Wu, W Zhang - Carbohydrate Polymers, 2024 - Elsevier
Wound healing is a complex process involving a complicated interplay between numerous
cell types and vascular systems. Hyaluronic acid (HA)-based hydrogel facilitates wound …

[HTML][HTML] Hyaluronidase promote transdermal diffusion of small sized curcumin nanocrystal by dissolving microneedles delivery

X Miao, J Zhao, H Xiang, X Shi - Pharmaceutics, 2023 - mdpi.com
Hyaluronidase is clinically used in treating many skin diseases due to its good permeability-
promoting effect, which may motivate the diffusion and absorption of drugs. To verify the …