[HTML][HTML] Using essential oils to overcome bacterial biofilm formation and their antimicrobial resistance

KA El-Tarabily, MT El-Saadony, M Alagawany… - Saudi Journal of …, 2021 - Elsevier
The increase of resistant bacteria puts a huge pressure on the antimicrobials in current use.
Antimicrobial resistance (AMR) results from antibiotic misuse and abuse over many years …

[HTML][HTML] Novel Antimicrobials for the Treatment of Clostridium difficile Infection

N Petrosillo, G Granata, MA Cataldo - Frontiers in medicine, 2018 - frontiersin.org
The current picture of Clostridium difficile infection (CDI) is alarming with a mortality rate
ranging between 3% and 15% and a CDI recurrence rate ranging from 12% to 40%. Despite …

Rapid bactericidal effect of cinnamon bark essential oil against Pseudomonas aeruginosa

ER Elcocks, PTN Spencer‐Phillips… - Journal of applied …, 2020 - academic.oup.com
Aims This study aimed to identify the most effective antimicrobial agent from a selection of
essential oils (EO) and investigate its bactericidal properties against Pseudomonas …

[HTML][HTML] Mechanism of Antibacterial Activity of Bacillus amyloliquefaciens C-1 Lipopeptide toward Anaerobic Clostridium difficile

J Lv, R Da, Y Cheng, X Tuo, J Wei, K Jiang… - BioMed Research …, 2020 - hindawi.com
Probiotics may offer an attractive alternative for standard antibiotic therapy to treat
Clostridium difficile infections (CDI). In this study, the antibacterial mechanism in vitro of …

Repurposing auranofin as a Clostridioides difficile therapeutic

ML Hutton, H Pehlivanoglu, CJ Vidor… - Journal of …, 2020 - academic.oup.com
Abstract Background Clostridioides difficile (previously Clostridium difficile) is the leading
cause of nosocomial, antibiotic-associated diarrhoea worldwide. Currently, the gold …

Faecal microbiota transplantation for recurrent C. difficile infections: challenges and improvement opportunities for clinical practice and healthcare systems

L Hocking, G Ianiro, RW Leong, T Iqbal… - Alimentary …, 2023 - Wiley Online Library
Background There is growing interest in faecal microbiota transplantation (FMT) as a
treatment for recurrent Clostridioides difficile infection (CDI), but evidence on the diverse …

In vitro anti-clostridial action and potential of the spice herbs essential oils to prevent biofilm formation of hypervirulent Clostridioides difficile strains isolated from …

A Aleksić, Z Stojanović-Radić, C Harmanus, EJ Kuijper… - Anaerobe, 2022 - Elsevier
Background Clostridioides difficile is the most common causative agent of antibiotic-
acquired diarrhea in hospitalized patients associated with substantial morbidity and …

[HTML][HTML] Effect of Bifidobacterium breve in combination with different antibiotics on Clostridium difficile

J Yang, H Yang - Frontiers in Microbiology, 2018 - frontiersin.org
While combinations of probiotics with antibiotics have exhibited beneficial and adverse
effects in the treatment of Clostridium difficile infection (CDI), no substantive explanation has …

Natural products show diverse mechanisms of action against Clostridium difficile

N Roshan, TV Riley, DR Knight, JH Steer… - Journal of applied …, 2019 - academic.oup.com
Aims To investigate the mechanisms of action of natural products with bactericidal
(cinnamon root powder, peppermint oil, trans‐cinnamaldehyde, menthol and zingerone) or …

Effect of natural products on the production and activity of Clostridium difficile toxins in vitro

N Roshan, TV Riley, DR Knight, KA Hammer - Scientific Reports, 2018 - nature.com
Clostridium difficile infection is a toxin-mediated disease of the colon. C. difficile virulence is
primarily attributed to the production of toxin A and toxin B; thus this study was aimed to …